Words similar to gefitinib

Example sentences for: gefitinib

How can you use “gefitinib” in a sentence? Here are some example sentences to help you improve your vocabulary:

William Pao and colleagues examined tumors from six patients with non-small cell lung cancer who initially responded to gefitinib or erlotinib but subsequently relapsed.
The mechanism of resistance in three patients was acquisition of a T790M substitution in EGFR that was not present at time of diagnosis, but was detected with progression of disease after initial response to gefitinib or erlotinib.
Whether KRAS mutational status can be used to predict responses to gefitinib or erlotinib in patients whose tumors have wild-type EGFR sequence is still under investigation: our analysis comparing response rates for tumors with neither EGFR nor KRAS mutations versus tumors with wild-type EGFR but mutated KRAS does not reach statistical significance (five of 22 versus zero of nine; p = 0.29).
In addition, only half of this small cohort of patients with NSCLC with clinical resistance to gefitinib or erlotinib had the T790M substitution.
All 17 tumors with EGFR mutations responded to gefitinib or erlotinib, while all nine tumors with KRAS mutations did not ( p = 3.2 × 10 −7 ).