Example sentences for: gcdca

How can you use “gcdca” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • 24 cells increased by 20 to 31% within 2 h of incubating the cells in medium containing 100 μM of glycine conjugates of cholic acid, chenodeoxycholic acid, and deoxycholic acid (GCA, GCDCA, GDCA, respectively) (Figure 4A).

  • GCDCA was the most potent in inducing the release of LDH among the bile acids tested whereas TCA had little effect as compared to the no addition controls.

  • 24 cells and primary mouse hepatocytes, through activation of the Fas receptor in a FasL-independent manner [ 19 25 ] . Moreover, GCDCA was demonstrated to activate both initiator and effector caspases, and that the apoptotic response can be blocked by Crm A, a caspase 8 inhibitor [ 25 ] . The mechanism by which bile acids stimulate the activation of Fas receptor remains unclear.

  • 24 cells [ 1 ] concordant with what has been documented in hepatocytes [ 19 ] . Consistent with the induction of apoptotic cell death; GCDCA, but not TCA, preferentially induced the activation of the initiator caspase 8 in McNtcp.

  • asbt, apical sodium/bile acid cotransporter; GCA, glycocholic acid; GCDCA, glycochenodeoxycholic acid; HBAB, human bile acid binder; LDH, lactate dehydrogenase; PI3K, phosphatidylinositol 3-kinase; TCA, taurocholic acid, TCDCA, taurochenodeoxycholic acid


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