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Example sentences for: gambian
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An exact test of population differentiation finds the observed haplotype distributions to be a poor fit of a model of random mating between the Gambian and Malawian samples, with a probability less than 10 -5.
For example, if the risk at SNP TNF+851 was 10, then the neighboring SNP, TNF+467, would give a relative risk of 3.7 in Malawi, but in the Gambian population, the effect would be protective with a relative risk of 0.8.
In a previous study, we described the nucleotide diversity of the TNF locus in 36 healthy, unrelated Gambian adults [ 13 ] . There we identified 11 SNPs by forward and reverse sequencing of the entire TNF gene from -1,389 bp relative to the start of transcription to +3,004 bp on 72 chromosomes.
In the Gambian sample, we observed 24 different haplotypes, and the distribution was dominated by one major haplotype (37.
For the Gambian and Malawian populations the F
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