Words similar to gain-of-function

Example sentences for: gain-of-function

How can you use “gain-of-function” in a sentence? Here are some example sentences to help you improve your vocabulary:

Genetic alterations such as amplification, deletion, translocation and rearrangement could result in either gain-of-function or loss-of-function mutations in genes that modulate aspects of cell proliferation, differentiation, motility and survival.
In theory, tab mutants could act downstream of or parallel to CDC15, and could be either loss-of-function mutations in genes that inhibit exit from mitosis or gain-of-function mutations in genes that promote exit from mitosis.
Excess GC activity due to LIFR loss is an unexpected result since LIF gain-of-function mice develop a Cushing's-like syndrome [ 29 30 ] . Thus, if the relationship were simple, loss of LIFR function would predict development of GC insufficiency.
A ribbon structure of erlotinib bound to the EGFR kinase domain (Figure 1) shows the threonine residue at position 790 in green and the positions of the exon 19 and L858R gain-of-function mutations.
This may be important for examining the effects of expressing gain-of-function or dominant-negative alleles of a gene product.