Words similar to gain-of-function

Example sentences for: gain-of-function

How can you use “gain-of-function” in a sentence? Here are some example sentences to help you improve your vocabulary:

A ribbon structure of erlotinib bound to the EGFR kinase domain (Figure 1) shows the threonine residue at position 790 in green and the positions of the exon 19 and L858R gain-of-function mutations.
This may be important for examining the effects of expressing gain-of-function or dominant-negative alleles of a gene product.
Although genetic manipulations involving gain-of-function point mutations of Smo [ 3 ] have demonstrated that the pathway can be activated independently of Hh ligand, no small molecules with this capability have been identified.
This procedure is an important addition to the available repertoire of molecular genetic techniques available to developmental biologists because it overcomes several deficiencies associated with alternative transient transgenic approaches normally used to study gain-of-function and dominant-negative alleles.
CFI1 ) [ 15 16 17 ] and that TAB6 is a gain-of-function mutation in CDC14 [ 18 ] . Net1 sequesters Cdc14 in the nucleolus and inactivates it in preanaphase cells.