Example sentences for: gain-of-function

How can you use “gain-of-function” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • CFI1 ) [ 15 16 17 ] and that TAB6 is a gain-of-function mutation in CDC14 [ 18 ] . Net1 sequesters Cdc14 in the nucleolus and inactivates it in preanaphase cells.

  • This procedure is an important addition to the available repertoire of molecular genetic techniques available to developmental biologists because it overcomes several deficiencies associated with alternative transient transgenic approaches normally used to study gain-of-function and dominant-negative alleles.

  • Furthermore, the gain-of-function Smo mutation renders the protein less sensitive to the inhibitors, presumably because the amino-acid substitution directly stabilizes or induces an active conformation.

  • Such a model cannot accommodate our observations with the gain-of-function Smo mutant.

  • Rabbits may provide an in vivo system for modeling some aspects of glaucoma, such as steroid induced ocular hypertension [ 23 24 25 26 27 ] and the gain-of-function hypothesis in POAG [ 42 ] .


How many words do you know? Try our free vocabulary size test!


Search

Search for example sentences

Loading Loading...
Quantcast