Words similar to gain-of-function

Example sentences for: gain-of-function

How can you use “gain-of-function” in a sentence? Here are some example sentences to help you improve your vocabulary:

In theory, tab mutants could act downstream of or parallel to CDC15, and could be either loss-of-function mutations in genes that inhibit exit from mitosis or gain-of-function mutations in genes that promote exit from mitosis.
A ribbon structure of erlotinib bound to the EGFR kinase domain (Figure 1) shows the threonine residue at position 790 in green and the positions of the exon 19 and L858R gain-of-function mutations.
The agonist, on the other hand, would be predicted to bind to a site on Smo that is not affected by this gain-of-function Smo actmutation.
This may be important for examining the effects of expressing gain-of-function or dominant-negative alleles of a gene product.
Somatic gain-of-function mutations in exons encoding the epidermal growth factor receptor (EGFR) tyrosine kinase domain are found in about 10% of non-small cell lung cancers (NSCLCs) from the United States [1,2,3], with higher percentages observed in east Asia [2,4,5,6].