Example sentences for: functional

How can you use “functional” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The clustering of functionally related genes in prokaryotic genomes into co-transcribed and co-regulated units, operons, often allows functional assignments through the principle of 'guilt by association' [ 30 31 32 ] . Generally, genes whose products physically interact to form a complex or are involved in successive steps in a biochemical pathway form operons that are conserved over large evolutionary distances [ 30 ] . On previous occasions, we have used gene neighborhoods or operons to predict novel DNA repair complexes and their components [ 33 ] . Accordingly, a similar approach was applied to the three families of SSAPs (RecT/Redβ, ERF, Rad52), to shed light on their functional links.

  • Because the duplications were identified through the similarity of full-length protein sequences (see Materials and methods), this procedure primarily, if not exclusively, detected functional genes rather than pseudogenes.

  • Concomitant with this development of asymmetrical structure, the AAA1 protomer of the dynein motor unit evolved a functional dominance, in which it alone retains the full ability for binding and hydrolysis of ATP, while AAA2, AAA3 and AAA4 have lost the capability for hydrolysis and the most degenerate protomers AAA5 and AAA6 show no significant binding of ATP [ 20 21 22 ] . In midasin, the specialization of AAA protomers appears to have taken a less drastic course than in dynein.

  • It is required, for instance, that arrows consistently distinguish: which (if there is more than one) of an icon's functional properties are affected either by context (as in cartoons) or by appearance (for example, double-weight arrows change concentration properties, by chemical reactions or transport, whereas single-weight arrows activate or inhibit activity properties); and how the property is affected (for example, filled heads mean 'increase', open heads mean 'decrease').

  • Translation, defined here as the conversion of an informationcarrying molecule into a corresponding encoded structure, enabled the expanded functional potential of proteins to be explored using powerful evolutionary methods that depend on the unique ability of nucleic acids to replicate.


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