Words similar to fti-

Example sentences for: fti-

How can you use “fti-” in a sentence? Here are some example sentences to help you improve your vocabulary:

Given the internally consistent actions of DN ROCK1 and CA ROCK1, as well as the results employing either FTI-1 or arachidonate, we concluded that the Y-27632 result might be due to inhibition by Y-27632 of protein kinases other than ROCK1 [23].
Since FTI-1 acts downstream of HMGCoA reductase, the stimulatory effect of FTI-1 on sAPP α shedding would not be predicted to be modified by mevalonate supplementation.
To test whether statin-activated shedding might be attributable to a metabolite downstream of HMGCoA reductase, cells were treated with 1 μM simvastatin, 5 μM FTI-1, and a series of concentrations of mevalonic acid.
FTI-1, an inhibitor of farnesyl transferase also known as L-744,832 [59], mimicked and potentiated statin-activated shedding, presumably by blocking transfer of isoprenoid moieties to a Rho protein by farnesyl transferase, and thereby decreasing Rho activity.
However, FTI-1 treatment can also increase the level of geranylgeranylated isoforms of certain Rho proteins, e.g., the inhibitory geranylgeranylated RhoB protein [60].