Words similar to fs-α

Example sentences for: fs-α

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The EC coupling recovered by fs-α 1S could be due either to the activity of the N-terminal half of α 1S alone or to protein-protein complementation between the N-terminal half and a fragment expressing the C-terminal half of α 1S . The C-terminal half of α 1S could have been translated by the fs-α 1S expression vector if the ATG codon (Met701), which is downstream from the TGA termination codon and is in-frame with the wild-type message (Fig 1B) served as open reading frame for translation of the second half of the wt message.
These observation suggests that the magnitude of the Ca 2+release appears to be limited by the low yield of expression of the C-terminal fragment achieved by leaky ribosomal scanning of the second half of the fs-α 1S message.
Thus, we are confident that the voltage-evoked Ca 2+transient in cells transfected by fs-α 1S cells was a direct consequence of the expressed protein.
Hence the signaling mechanism, like that reported in normal myotubes and dysgenic myotubes expressing wt-α 1S , was Ca 2+entry independent [ 29 ] . We also expressed fs-α 1S in cultured myotubes from two available gene knock-out (KO) mice, lacking the endogenous β1a isoform of the skeletal muscle DHPR [ 30 ] and lacking RyR1 [ 31 ] . As shown in Fig.
pSG5 fs-α 1S