Example sentences for: fs-α

How can you use “fs-α” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The C-terminal fragment was generated by an unusual restart of translation of the fs-α 1S message at M701, presumably by leaky ribosomal scanning, and was eliminated by a M701I mutation.

  • However, when myotubes were cotransfected with fs-α 1S M701I and α 1S Δ1-700, each in a separate pSG5 vector, there was a robust recovery of Ca 2+transients in 5 of 5 cells.

  • If fs-α 1S recovered EC coupling by virtue of expressing a single protein fragment, then fs-α 1S M701I should also recover EC coupling since the mutation was introduced downstream from the stop codon.

  • Except for the magnitude, the SR Ca 2+release signal expressed by fs-α 1S was entirely typical of skeletal myotubes with sigmoidal voltage-dependence, proceeding in the absence of external Ca 2+and requiring RyR1.

  • 3shows that fs-α 1S recovered a significant fraction of the voltage-activated Ca 2+transient compared to that express by full-length wt-α 1S . The magnitude of the fluorescence signal expressed by fs-α 1S was approximately 5-fold larger than the largest Ca 2+transient detected in non-transfected myotubes expressing Idys, >20-fold larger than the average Ca 2+transient detectable in non-transfected cells, and about 1/3 of the maximum SR Ca 2+release expressed by the control wt-α 1S construct.


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