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Example sentences for: from
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A variety of environmental small molecules, namely, nutrients, xenobiotics and first messengers are recognized by cells, with the help of specialized protein sensors on their surfaces [ 1 2 ] . Additionally cells also use protein-bound small molecules, such as FAD, cinnamic acid, tetrapyrroles and heme as sensors of photons and the ambient redox states [ 3 4 ] . Within cells, small molecules, such as cyclic nucleotides, are used as intracellular messengers to transduce signals arising from a variety of stimuli [ 1 2 ] . Over the past few years a combination of protein sequence analysis and biochemical studies have revealed several unifying principles that govern the recognition of small molecules by cells [ 4 5 6 7 8 9 ] . A significant component of small molecule-protein interactions is mediated via a relatively small set of ancient conserved protein domains that bind their ligands using specialized pockets [ 4 10 ] . Certain protein folds have given rise to several large superfamilies of ligand-binding domains.
The main story in the British press Thursday was the suspension from competition of Linford Christie, the 1992 Olympic gold medal winner for the 100 meters, after he tested positive for the steroid nandrolone at a German event.
4Industry provided 470 comments, 86 were received from trade associations, 60 from environmental groups, 1,875 from private citizens, 5 from other federal agencies, 60 from state agencies, 108 from public interest groups, 18 from labor groups, 14 from universities, and 36 from associations.
In an accompanying paper, C. Bergman et al . [ 65] surveyed sequence conservation in approximately 0.5 Mb of the D. melanogaster genome containing 81 genes using comparative data from four Drosophila species ( D. erecta, D. pseudoobscura, D. willistoni and D. littoralis) . Their comparison to our D. melanogaster annotations detected no genes conserved in other species that were missed in Release 3 [ 65].
13For guidance in measuring and reporting the cost of heritage assets transferred from other federal entities, and heritage assets acquired through donation or devise, see the general PP&E standard contained in Accounting for Property, Plant, and Equipment, SFFAS No.
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