Words similar to free-energy

Example sentences for: free-energy

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We further elaborated this hypothesis by comparing the lowest free energy structures of the donor- and acceptor sites of all exons that were prone to skipping (bold in Table 1) to their first higher free-energy structures using the mfold program [ 26 27 ] . Some structures showed remarkable alterations between both energy states, but many others did not at all.
Recently, it was suggested that NF1 exon skipping events could be explained by structural alterations in possible higher free-energy structures of the pre-mRNA at the donor site [ 19 ] . Here in, it was hypothesised that when an alternative structure is too different from the lowest free-energy structure (ground state) this sequence is not recognised by the splicing machinery and that, as a consequence, the corresponding exon becomes skipped.