Words similar to free-energy

Example sentences for: free-energy

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Recently, it was suggested that NF1 exon skipping events could be explained by structural alterations in possible higher free-energy structures of the pre-mRNA at the donor site [ 19 ] . Here in, it was hypothesised that when an alternative structure is too different from the lowest free-energy structure (ground state) this sequence is not recognised by the splicing machinery and that, as a consequence, the corresponding exon becomes skipped.
We further elaborated this hypothesis by comparing the lowest free energy structures of the donor- and acceptor sites of all exons that were prone to skipping (bold in Table 1) to their first higher free-energy structures using the mfold program [ 26 27 ] . Some structures showed remarkable alterations between both energy states, but many others did not at all.