Words similar to frataxin
Example sentences for: frataxin
How can you use “frataxin” in a sentence? Here are some example sentences to help you improve your vocabulary:
Normal mitochondrial iron homeostasis minimally depends on wild-type frataxin to control efflux.
Yfh1p (YDL120W), the frataxin homolog in yeast, interacts with the yeast mitochondrial intermediate peptidase (Oct1, YKL134C) to lower matrix iron concentration, directly and by competition [ 33].
Lack of frataxin protein causes a build-up of iron in the matrix spaces of the mitochondria.
Both proteolytic cleavage (via MPP and/or IMP complexes) and chaperonin help (mt-HSP70/Ssc2p) in membrane trafficking and/or folding are needed for the mature frataxin protein to arrive at its destination in the matrix in its proper conformation.
The shortage of frataxin does not result from formation of mutant proteins, but rather from expansion of a GAA repeat in the first intron of the frataxin gene.