Words similar to frameshift

Example sentences for: frameshift

How can you use “frameshift” in a sentence? Here are some example sentences to help you improve your vocabulary:

In a second case, a 10 bp deletion in exon 2 causes a frameshift at Met48, leading to incorporation of 12 new residues and a stop codon [ 25].
Some cases of HSP result from mutations in the gene for paraplegin, a nuclear-encoded mitochondrial metalloprotease, including: a 2 bp deletion at position 784, which causes a frameshift that eliminates 60% of the protein; and an adenine insertion at position 2,228 of the paraplegin cDNA, which creates a frameshift resulting in truncation of the last 57 residues of this 795-residue protein [ 37].
It is possible that the frameshift mutations seen in deafness-dystonia interfere with the interface between Tim8p and Tim13p.
This mutation, common among families with hereditary ovarian cancer, is a frameshift mutation occurring at the beginning of the C 3 HC 4 region of exon 2 that essentially interrupts RING domain function [ 19 29 30 ] . The results showed that disruption of the BRCA1 amino-terminal RING domain altered caspase 3 activation and subsequent DFF45 and PARP cleavage, resulting in accelerated STS-induced apoptosis.
Poor-quality sequences often present as novel singleton hits that closely resemble known genes, but encode potential proteins that are missing key residues, or contain apparent stop codons or frameshift mutations within functionally important regions.