Example sentences for: frameshift

How can you use “frameshift” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Whole pseudogenes were found by searching for matches to SWISS-PROT protein sequences in intergenic DNA, and are usually characterized by frameshift mutations or early stop codons that prevent normal transcription or translation [ 18, 19].

  • Probable pseudogenes were identified on the basis of the presence of a poly(A) tail at the 3' end of corresponding genomic sequences, the presence of internal stop codons or the presence of frameshift mutations within the catalytic domain.

  • In two cases seen to date, a 1 bp deletion in exon 1 (T151del) results in a frameshift, leading to incorporation of 25 new amino acids after Glu38, followed by a stop codon.

  • These include missense and frameshift (+/-1 or +/-2 nucleotide difference) changes in the predicted ORF relative to the Release 3 predicted protein.

  • A single nucleotide deletion at position 105 of the homologous region results in a frameshift and the computer-deduced amino-acid sequence uses a start codon located 12 residues upstream from that point mutation.


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