Example sentences for: frameshift

How can you use “frameshift” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Comparison of the levels of synonymous (amino-acid preserving) and non-synonymous (amino-acid altering) nucleotide mismatches, between hits containing unverifiable stop codons or frameshift mutations and the most similar registered EPK, was used to identify additional probable pseudogenes and sequencing artifacts.

  • This would result in an out-of-frame translation with the NIP2;1 -like coding sequence for 35 residues upstream of the position of the frameshift.

  • The presence of internal stop codons or frameshift mutations was used to identify pseudogenes, but only if the feature could be verified in a sequence derived from a different cloning library.

  • The frameshift mutation leading to the truncated sequence of Cpn 010 was identified in CWL029 and 4 other isolates: AR388, AR231, KA5C and KA66 (not shown).

  • This mutation, common among families with hereditary ovarian cancer, is a frameshift mutation occurring at the beginning of the C 3 HC 4 region of exon 2 that essentially interrupts RING domain function [ 19 29 30 ] . The results showed that disruption of the BRCA1 amino-terminal RING domain altered caspase 3 activation and subsequent DFF45 and PARP cleavage, resulting in accelerated STS-induced apoptosis.


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