Words similar to frameshift
Example sentences for: frameshift
How can you use “frameshift” in a sentence? Here are some example sentences to help you improve your vocabulary:
Comparison of the levels of synonymous (amino-acid preserving) and non-synonymous (amino-acid altering) nucleotide mismatches, between hits containing unverifiable stop codons or frameshift mutations and the most similar registered EPK, was used to identify additional probable pseudogenes and sequencing artifacts.
This would result in an out-of-frame translation with the NIP2;1 -like coding sequence for 35 residues upstream of the position of the frameshift.
The presence of internal stop codons or frameshift mutations was used to identify pseudogenes, but only if the feature could be verified in a sequence derived from a different cloning library.
The frameshift mutation leading to the truncated sequence of Cpn 010 was identified in CWL029 and 4 other isolates: AR388, AR231, KA5C and KA66 (not shown).
This mutation, common among families with hereditary ovarian cancer, is a frameshift mutation occurring at the beginning of the C 3 HC 4 region of exon 2 that essentially interrupts RING domain function [ 19 29 30 ] . The results showed that disruption of the BRCA1 amino-terminal RING domain altered caspase 3 activation and subsequent DFF45 and PARP cleavage, resulting in accelerated STS-induced apoptosis.