Example sentences for: frameshift

How can you use “frameshift” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The length (from UNIX wc command) divided by 3 was used to validate the absence of frameshift errors.

  • This mutation, common among families with hereditary ovarian cancer, is a frameshift mutation occurring at the beginning of the C 3 HC 4 region of exon 2 that essentially interrupts RING domain function [ 19 29 30 ] . The results showed that disruption of the BRCA1 amino-terminal RING domain altered caspase 3 activation and subsequent DFF45 and PARP cleavage, resulting in accelerated STS-induced apoptosis.

  • The nucleotide sequence of each hit that contained unverifiable stop codons or frameshift mutations was further analyzed by comparing the nucleotide sequence of the hit to the nucleotide sequence of closely related known EPKs.

  • Given the fact that the premature termination codons resulting from the frameshift mutations are all located in the 3' final exon of the MECP2 gene, preferential degradation of nonsense codon-containing transcripts would not be expected [ 24 ] .

  • In two cases seen to date, a 1 bp deletion in exon 1 (T151del) results in a frameshift, leading to incorporation of 25 new amino acids after Glu38, followed by a stop codon.


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