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The health benefits or hazards associated with fish consumption will require added attention to origin of fish - marine or fresh water - given the reported differences in stores of polyunsaturated fatty acids and N-3 fatty acid between the two types of fish [ 44 45 46 47 ] . Levels of N-3 fatty acids vary by fish species, oil content of fish, sex and age of fish, and factors exogenous to fish such as water temperature [ 47 48 ] . Oily fish from cold waters (whether marine or fresh bodies of water) are reported to have higher levels of N-3 fatty acids in comparison to fish from warmer bodies [ 45 47 ] . The ratio of N-3 to N-6 fatty acids has recently been suggested as being associated with gestation and birth weight [ 49 ] and this ratio is approximately four-times greater in marine fish in comparison to fresh water fish [ 45 ] . Type and species-specific fish consumption will remain important considerations in assessing exposure scenarios based on fish consumption.