Words similar to forskolin
Example sentences for: forskolin
How can you use “forskolin” in a sentence? Here are some example sentences to help you improve your vocabulary:
On the other hand, it has been previously demonstrated that direct activation of adenylate cyclase by Forskolin or cholera toxin, inhibition of cAMP-specific phosphodiesterase, and treatment with a cell permeable cAMP analog, induces a rise in intracellular cAMP [ 22 23 24 25 26 ] . Since cAMP is known to modulate the expression of CD8 in mice [ 27 ] , we sought to determine whether cAMP-dependent protein kinase (PKA)-mediated signaling plays a role in modulating the mRNA levels of CD3, CD4, and CD8 in ex vivo examined human thymocytes.
Inhibition of Forskolin stimulated cyclic AMP (cAMP) production by exposure to increasing concentrations of agonists were evaluated in intact cells.
The efficacy of each ligand was defined as percent inhibition of forskolin stimulated cAMP production compared to no ligand levels (0% inhibition, 100% cAMP production).
The inhibitory action of 4-AP on progesterone production was investigated further using not only primary cultures, but also the spontaneously established granulosa cell line, PGC-2 [ 19 ] . Although PGC-2 lack FSH receptors, these cells can serve as a useful in vitro model for GC function, because they produce cAMP in response to forskolin and synthesize progesterone and estradiol when supplied with appropriate substrates.
Stock solutions of forskolin (10 mM) and 3-isobutyl-1-methylxanthine (IBMX, 80 mM) were in DMSO.