Words similar to forskolin
Example sentences for: forskolin
How can you use “forskolin” in a sentence? Here are some example sentences to help you improve your vocabulary:
Our prior studies showed that increases in cGMP by nitrovasodilators and cAMP by forskolin increase ser 16-HSP20 phosphorylation and induce force suppression [ 8 ] . Such results suggest that the correlation between ser 16-HSP20 phosphorylation and force suppression is robust in the swine carotid stimulated with 10 μM histamine.
Furthermore, this supports the data showing that the agonist can activate signaling in Shh -/-embryos (Figure 3) and suggests that the agonist function is not only downstream of the Hh protein but also independent of the endogenous Hh-signaling modulators, Tout veloux and HIP, that act via the Hh ligand [ 2 ] . The competition experiment with forskolin showed identical inhibition curves for Hh protein and the agonist, strongly suggesting that the action of the small molecule is upstream of the protein-kinase-A-sensitive step in the pathway.
The Hh-blocking antibody 5E1 had no effect on pathway activation by the agonist (Figure 4b), while forskolin (Figure 4c), cyclopamine (Figure 4d) and Cur61414 (Figure 4e), were all inhibitory.
The inhibitory action of 4-AP on progesterone production was investigated further using not only primary cultures, but also the spontaneously established granulosa cell line, PGC-2 [ 19 ] . Although PGC-2 lack FSH receptors, these cells can serve as a useful in vitro model for GC function, because they produce cAMP in response to forskolin and synthesize progesterone and estradiol when supplied with appropriate substrates.
Inhibition of Forskolin stimulated cyclic AMP (cAMP) production by exposure to increasing concentrations of agonists were evaluated in intact cells.
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