Example sentences for: forskolin

How can you use “forskolin” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • On the other hand, it has been previously demonstrated that direct activation of adenylate cyclase by Forskolin or cholera toxin, inhibition of cAMP-specific phosphodiesterase, and treatment with a cell permeable cAMP analog, induces a rise in intracellular cAMP [ 22 23 24 25 26 ] . Since cAMP is known to modulate the expression of CD8 in mice [ 27 ] , we sought to determine whether cAMP-dependent protein kinase (PKA)-mediated signaling plays a role in modulating the mRNA levels of CD3, CD4, and CD8 in ex vivo examined human thymocytes.

  • After addition of forskolin, the cells were incubated for 15 additional minutes.

  • Inhibition of Forskolin stimulated cyclic AMP (cAMP) production by exposure to increasing concentrations of agonists were evaluated in intact cells.

  • Stock solutions of forskolin (10 mM) and 3-isobutyl-1-methylxanthine (IBMX, 80 mM) were in DMSO.

  • After 24 h the medium was replaced with serum-free medium containing either pregnenolone (1 μg/ml), androstenedione (100 μM), 5α-dihydrotestosterone (5α-DHT, 10 or 100 μM), or forskolin (5 μM) and IBMX (10 μM).


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