Words similar to forskolin
Example sentences for: forskolin
How can you use “forskolin” in a sentence? Here are some example sentences to help you improve your vocabulary:
Following 15 minutes incubation, forskolin was added to each well to a final concentration of 5 μM followed by another incubation for 15 min at 37°C.
Forskolin, fentanyl, IBMX, hydromorphone, and naltrexone were obtained from Sigma-Aldrich (St.
Thus the data from several experiments were normalized to the top of the fitted curve (no ligand, forskolin alone), the results of several experiments pooled and a new fitted curve constructed (Figure 2).
Furthermore, this supports the data showing that the agonist can activate signaling in Shh -/-embryos (Figure 3) and suggests that the agonist function is not only downstream of the Hh protein but also independent of the endogenous Hh-signaling modulators, Tout veloux and HIP, that act via the Hh ligand [ 2 ] . The competition experiment with forskolin showed identical inhibition curves for Hh protein and the agonist, strongly suggesting that the action of the small molecule is upstream of the protein-kinase-A-sensitive step in the pathway.
The inhibitory action of 4-AP on progesterone production was investigated further using not only primary cultures, but also the spontaneously established granulosa cell line, PGC-2 [ 19 ] . Although PGC-2 lack FSH receptors, these cells can serve as a useful in vitro model for GC function, because they produce cAMP in response to forskolin and synthesize progesterone and estradiol when supplied with appropriate substrates.