Words similar to foreskin
Example sentences for: foreskin
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foreskin fibroblasts, the ATM was estimated to be 360 kD, consistent with the results previously described [ 12 13 ] . In three rhabdomyosarcoma cell lines (RD, Rh28 and RH30), there was one aberrant form of ATM protein (~260 kD) that was significantly smaller than that seen in the normal fibroblasts and the Hela cells (Fig 5).
Throughout these studies, human adult MSCs and foreskin fibroblasts were used as positive and negative controls, respectively.
Unsupervised hierarchical cluster analysis of genes and experiments of 9 normal genital skin fibroblast lines (penile foreskin) and 5 AIS genital skin fibroblast lines (labia majora).
WNT2 (wingless-type MMTV integration site family member 2) was part of a small gene cluster with high expression in normal male foreskin fibroblasts that distinguished these samples from all other fibroblasts (Figure 2).
Several genes expressed specifically in the normal male foreskin fibroblasts have been previously implicated in male genital development, including HOXA13 , the T-box genes, BMP4 and DWnt2 . Mutations in HOXA13 can cause distal limb and urogenital-tract malformations such as male hypospadias in hand-foot-genital syndrome [ 21 ] . T-box genes ( TBX ) are essential early regulators of limb development and also appear to be involved in male genital development [ 22 23 ] . Mutations in TBX3 cause the ulnar-mammary syndrome characterized by limb, apocrine, and genital developmental abnormalities [ 23 ] . Expression of T-box genes 2, 3, and 5 was significantly higher in normal male foreskin fibroblasts than in AIS genital fibroblasts.
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