Example sentences for: forebrain

How can you use “forebrain” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Additionally, Nac expression in the mouse forebrain promoted formation of radial glia, the earliest specificied cell type in forebrain [ 32] and either permitted [ 33] or promoted gliogenesis in the peripheral nervous system [ 34].

  • The possibility that domoic acid may activate neonatal microglia both in vitro and in vivo is suggested by recent observations with kainic acid, a domoic acid and glutamate analog that can induce upregulation of neonatal microglia scavenger receptor mRNA [ 22 ] and tissue plasminogen activator release [ 23 ] . The putative molecular explanation for these observations has been that kainic acid activates the ionotropic AMPA glutamate GluR4 subunit which has recently been shown to be expressed by activated microglia following transient forebrain ischemia in vivo [ 24 ] . Because this subunit of the AMPA glutamate receptor has affinity for domoic acid [ 25 26 27 ] , we hypothesized that domoic acid might activate neonatal microglia in vitro and lead to concomitant mediator release [ 21 ] .

  • The site of origin of these cells in the olfactory placode, as well as the time course and migratory route along the olfactory nerve (ON) and into the forebrain are well documented [ 11 12 13 14 ] . Previous work in the laboratory has shown that olfactory axons emerge from the olfactory epithelium at stage 18 and are first joined by glia [ 15 ] and GnRH neurons [ 16 ] at stage 21.

  • [ 5 ] reported a timetable in which, if the insult occurs before the tenth embryonic week (in humans), all forebrain commissures will be absent.

  • The promoter of the Ogg1 gene does not have a TATA box [ 40 ] , but Ogg1 is differentially expressed in the rat CNS, and its expression is increased after mouse forebrain ischemia-reperfusion [ 35 36 ] , suggesting that regulation occurs, either at the transcriptional or post-transcriptional level.


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