Example sentences for: footprinting

How can you use “footprinting” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • DNase I footprinting assays were carried out in 30 μl of binding buffer (1 mM Tris, pH7.

  • Subsequently, sequence analysis identified KRC as a member of the ZAS family of proteins which share the ability to bind κB-like motifs [ 15 ] . DNA competition analysis showed that KRC fusion proteins containing the ZAS-C domain bind specifically to both the RSS and to the κB motif [ 14 28 ] . DNA footprinting analysis further showed that KRC/ZAS-C binds to specific nucleotides within the κB and the heptamer of the RSS [ 14 ] . In this study, using a PCR-based DNA-binding site-selection and amplification procedure, we demonstrated that both the N-terminal ZAS-N and the C-terminal ZAS-C domains are able to bind GT-rich DNA sequences, and confirmed that the RSS and κB motifs are the high-affinity targets of KRC.

  • The DNA binding specificity of the ZAS-N or ZAS-C domains from several ZAS members have been characterized by electrophoretic mobility shift assays, methylation interference experiments, and DNAse I footprinting experiments.

  • These NarL-phosphate protections extended from position -59 to +38, consistent with the results of the DNase I footprinting experiments described above.

  • Consequently, we expanded the focus of phylogenetic footprinting from the conservation of contiguous sequences to higher-order features of TCRs, namely the spatial organization of individual binding sites.


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