Words similar to fmlp
Example sentences for: fmlp
How can you use “fmlp” in a sentence? Here are some example sentences to help you improve your vocabulary:
And Wang [ 16 ] reported that U73343 suppressed elevation of [Ca 2+] i in neutrophils challenged with FMLP in the presence, but not the absence, of extracellular Ca 2+Both reports are consistent with a lack of effect of U73343 on receptor-mediated activation of PLC and a direct inhibitory effect on Ca 2+influx pathways in these cells.
Previous reports have demonstrated that ADP-ribosylation of B-lymphoid cell lines by C3 treatment inhibits phorbol ester induced cellular homotypic aggregation [ 18 ] . Also, phorbol ester and chemoattractant (IL-8 and fMLP) induced pre-B lymphoblastoid adhesion to VCAM-1 and neutrophil adhesion to fibrinogen was abrogated in a dose-dependent manner by C3 exoenzyme [ 36 ] . This may indicate that in cells of hematopoietic lineages, the induction of an increased adhesive state may be susceptible to regulation by Rho proteins.
To determine whether acute endotoxemia activated adherent vascular lung neutrophils for increased functional responsiveness, we initially analyzed their chemotactic activity towards bacterially-derived fMLP.
Chemotactic responsiveness of lung neutrophils towards bacterially-derived n-formyl-methionyl-leucyl-phenylalanine (fMLP) was quantified using a Neuroprobe 48-microwell chemotaxis chamber and 5-μm pore size Nucleopore filters [ 12 13 ] . Cells (2 × 10 6cells/ml), suspended in HBSS containing 0.5% BSA, were incubated in the upper wells of the chamber at 37°C with fMLP (50 nM) or medium in the lower wells.
Induction of acute endotoxemia resulted in a dramatic increase in their responsiveness to fMLP, which was evident in cells isolated 0.5 hours after treatment of the animals (Fig.
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