Words similar to flavopiridol

Example sentences for: flavopiridol

How can you use “flavopiridol” in a sentence? Here are some example sentences to help you improve your vocabulary:

Given the demonstration that flavopiridol is a global transcriptional inhibitor, we wished to understand the selective activity of flavopiridol against certain cancer types in vivo . Clearly, genes with short mRNA half-lives would be most rapidly and quantitatively inhibited by flavopiridol, and thus we wished to assign the genes with short half-lives in OCI-Ly3 cells to functional classes.
First, we utilized the small molecule cyclin-dependent kinase inhibitor, flavopiridol, which at low concentrations (e.g.
The following additional data files containing the primary data for the figures are included with this article: Figure 1a, flavopiridol titration ( Excel csv file); Figure 1c, Cdk inhibitors ( Excel csv file); Figure 2a, flavopiridol, actinomycin D and DRB ( Excel csv file); Figure 3, half-lives of well-measured genes ( Excel csv file); Figure 4a, proliferation genes ( Excel csv file); Figure 4b, anti-apoptotic genes ( Excel csv file); Figure 4d, induced genes in OCI -Ly3 cells ( Excel csv file); Figure 5c, highly induced genes in PBMC ( Excel csv file); Figure 5d, highly induced chemokines, cytokines and their receptors ( Excel csv file).
Further, the similar effects of flavopiridol and DRB argue that the predominant effect of flavopiridol on gene expression results from its ability to inhibit P-TEFb.
The initial impetus of this research was to understand the mechanism of action of the anti-cancer drug flavopiridol.