Words similar to firstly
Example sentences for: firstly
How can you use “firstly” in a sentence? Here are some example sentences to help you improve your vocabulary:
Firstly, this study was initiated to help to determine the causes of major morbidity and mortality after hepatobiliary surgery, such that we might alter our patient care in order to avoid similar complications in the future.
Among the intrinsic factors underlying asymmetric division, the interactions of the Numb differentiation-associated protein with Notch proliferation-associated signaling is the model most widely studied, ranging from bacteria, yeast, and Drosophila to mammals [ 30 ] . When the neuronal progenitor cells undergo asymmetric division (20% in neuronal tissue cell culture) they produce neuronal daughter cells to which Numb protein segregates preferentially, and such daughter cells show an enhanced differentiation of neuronal processes [ 45 ] . Interestingly, Numb is firstly associated with one pole of the plasma membrane of a dividing cell, and subsequently with one of the two resulting nuclei [ 29 45 ] . Our study indicates that preservation of nuclear ERα in one of two postmitotic cells is associated with the ability of CT to replicate and diminution of ERα and appearance of nuclear ERβ dictates a generation of a daughter cell that is committed to differentiate (Fig.
Firstly, its human U95 series chip consists of 5 chip types with 12,000 coding clusters each, which makes it expensive to profile all the human genes in samples of interest.
Two relatively novel concepts for Hh signaling are raised by these GPCR models: firstly, the importance of considering the active Smo-coupler/effector complexes when modeling pathway regulation, and secondly the potential for endogenous ligands in the regulation of Smo activity.
Firstly, the p53 in TM10 (p53 wt) cells might have been acetylated upon treatment with 2.5 μM SAHA for 2 or 3 days.
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