Example sentences for: first

How can you use “first” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Chatterbox at first thought this was an adventurous metaphor for the way Blumenthal's story had been eclipsed by the news from Iraq, or the lull in the Flytrap scandal, or by Broder's own attitude.

  • on or after January 1 of the fifth year before the first covered year, then"adjusted baseline heat input" shall mean the average annual heat input used by the unit during the fifth and fourth years before the first covered year; and

  • The first, the ER overload response, triggers the activation of the transcription factor NFkB and the subsequent upregulation of inflammatory proteins [ 13 ] . The second, the unfolded protein response (UPR) induces three divergent cellular events: (i) the activation of transcription factor ATF6 leading to the upregulation of ER chaperones such as protein disulfide isomerase, (ii) upregulation of the pro-apoptotic transcription factor GADD153 and (iii) suppression of protein synthesis via phosphorylation of eukaryotic translation initiation factor 2α (eIF2α) by pancreatic eIF2α kinase (PEK/PERK, [ 11 12 ] ). Upregulation of the ER chaperones, GADD153 and PERK in response to a toxic insult would constitute direct evidence of an ER stress response.

  • First, Rec12 may be required for an "MI nondisjunction checkpoint" that delays meiotic cells in which proper MI disjunction has failed to occur.

  • Predictably, the NYT story is sourced to "White House officials" and "aides" in the first few paragraphs; oddly enough, it quotes Bruce Reed (Clinton's chief domestic policy advisor) by name at the end.


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