Example sentences for: fine-tuning

How can you use “fine-tuning” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The late appearance of MHCK-C during furrowing suggests a cellular mechanism regulating its localization, and our biochemical data suggest that MHCK-C phosphorylation levels may represent a mechanism for the fine-tuning of the activity of MHCK-C in the cleavage furrow during cell division.

  • The fine-tuning of gene expression to permit such diversity remains largely uncharacterized.

  • Even when Keynesian macroeconomists were at their most hubristic, none of them claimed that macroeconomic "fine-tuning" could make an economic jalopy into a Porsche.

  • The Insider leaves viewers with the impression that it was Wigand who first told America that the tobacco industry was fine-tuning the way cigarettes delivered nicotine to the body.

  • It has been demonstrated that malignant tissues with accelerated cell cycle show higher levels of ProTα expression than normal or surrounding healthy tissues [ 67 ] . ProTα was shown as a marker for breast cancer [ 68 ] , hepatocarcinoma [ 69 ] , and plasma levels of its derivative Tα 1 been proposed as a marker for the prognosis of lung cancer [ 70 ] . In ligand blotting assays, ProTα bound only to chromatin pools and nuclear fractions where histone H1 was present [ 71 72 ] . The analysis of the interaction of ProTα with H1-containing chromatin suggests a putative role for ProTα in the fine-tuning of the stoichiometry and/or mode of interaction of H1 with chromatin [ 73 ] . Interestingly, HL-60 cells overexpressing ProTα show an enhancement of accessibility of micrococcal nuclease to chromatin, implying relaxed chromatin structure for enhanced cell cycle gene expression [ 74 ] .


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