Words similar to fibrillin-

Example sentences for: fibrillin-

How can you use “fibrillin-” in a sentence? Here are some example sentences to help you improve your vocabulary:

Primary fibroblast cultures from patients and control individuals were grown to confluency and then metabolically labeled with 35S-cysteine as described [ 17 18 ] . The soluble cell lysis fraction, containing newly synthesized labeled fibrillin-1 molecules, and the insoluble fraction, representing the labeled fibrillin in the extracellular matrix, were fractionated by SDS polyacrylamide gel electrophoresis and autoradiographed.
Labeled fibrillin-1 was identified and quantified as described [ 17 18 ] . More recently, the results were replicated by use of a phosphorimager.
The levels of fibrillin-1 production and deposition in the extracellular matrix were expressed as the percentage of values obtained for simultaneously studied normal control fibroblast cultures.
Thus, it appears that deletion of three contiguous EGF-like domains can have different effects depending on their location within the fibrillin-1 molecule.
The deposition of newly synthesized fibrillin into the matrix was greatly reduced (13 % of normal), however, suggesting that the internally deleted mutant fibrillin-1 molecules are secreted and exert a dominant-negative effect on extracellular microfibril assembly.