Words similar to fda-positive
Example sentences for: fda-positive
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The second data set used to estimate unexposed incidence rates was the control groups of the studies listed in table 1. Cases of FDA-positive AR and MR reported in the control groups were assumed to have arisen between age 40 and the average age of the control group in each study.
For example, without making any adjustments to observed prevalence rates, Loke, et al [ 18 ] reported a summary "relative risk" of 2.82 (95% CI 2.20 - 3.61, z = 8.21, p < 0.0001) for FDA-positive AR and 1.55 (95% CI 1.06 - 2.25, z = 2.28, p = 0.02) for MR utilizing most of the same studies included in the present report.
While two studies performed echocardiograms one year apart in sizable populations, both showed either no net progression or a net decrease in regurgitation in the unexposed, control groups [ 24 25 ] . These findings underscore the infrequency of new onset, FDA-positive AR or MR in the unexposed population.
Prior summary estimates of risk for developing FDA-positive AR and MR have been based on simple comparisons of prevalence in persons exposed and unexposed to anorexic drugs.
Data provided in this study can be used to estimate the relative contribution of exposure to fenfluramines to overall incidence of echocardiographically defined, FDA-positive AR and MR. Given that approximately 2.5% of the population of the United States had used anorexic prescription drugs (mostly fenfluramine and dexfenfluramine) between 1996 and 1998 [ 30 ] , approximately 32% and 11% of all FDA-positive AR and MR respectively could be attributed to fenfluramine or dexfenfluramine use.
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