Words similar to family-based
Example sentences for: family-based
How can you use “family-based” in a sentence? Here are some example sentences to help you improve your vocabulary:
Further, this implies that putative Ch6p alleles associated with CVID or IgGSD susceptibility occur on many HLA haplotypes that are common in Caucasians in central Alabama [ 10 ] and in Caucasians from a large national bone marrow donor program [ 14 ] . The present observations also confirm and extend the reports of association of HLA haplotype A*01-B*08 (or an extended haplotype containing A*01 and B*08) with heritable forms of immunoglobulin deficiency demonstrated in family-based analyses [ 3 6 19 20 21 22 ] . It is likely that a candidate gene(s) for CVID or IgGSD exists in the HLA class II region, [ 6 19 20 21 22 23 ] . Because the class II region is closer to the HLA-B locus than to the HLA-A locus, it is plausible that candidate gene(s) for CVID or IgGSD in the class II region are in greater linkage disequilibrium with HLA-B than HLA-A.
Based on 7 case control studies (4 positive) and 14 family-based studies (9 positive), the meta analysis concluded that a "..
.statistically significant association between ADHD and the 7-repeat allele of DRD4" existed, with a relative risk of 1.9 for 7 case-control studies and 1.4 for 14 family-based studies.
Subjects homozygous for the 10-repeat allele showed significantly lower dopamine transporter binding than carriers of the 9-repeat allele [ 47 ] . Cook [ 48 ] summarized the results of an additional 11 family-based studies in a meta analysis and concluded that the association between the DAT gene and ADHD was highly significant (p < .0001).
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