Example sentences for: familial

How can you use “familial” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Familial and epidemiological studies have indicated that there is a strong genetic component in the aetiology of diabetic nephropathy in Type I diabetes patients [ 1, 2].

  • Common variable immunodeficiency (CVID) and selective immunoglobulin G subclass deficiency (IgGSD) are characterized by subnormal serum concentrations of total IgG, or by normal serum total IgG concentrations with deficiency of one or more IgG subclasses, respectively; in some cases, IgA or IgM levels are also subnormal [ 1 2 3 ] . Most persons are diagnosed to have CVID or IgGSD because they have increased frequency and severity of infections due to bacteria and other microbial pathogens [ 1 4 ] . Although a susceptibility locus for these disorders has not been identified, they often appear to be familial and to segregate with markers on Ch6p [ 1 5 6 ] .

  • In addition to DCM with conduction system disease and variable skeletal muscle involvement, mutations in the Lamin A/C gene [OMIM 150330] have been shown to cause autosomal dominant [ 11 ] and autosomal recessive [ 12 ] Emery-Dreifuss Muscular Dystrophy (EDMD), autosomal dominant limb-girdle muscular dystrophy type 1B (LGMD) [ 13 ] , autosomal recessive type 2 Charcot-Marie Tooth type 2 [ 14 ] , familial partial lipodystrophy [ 15 16 ] , Mandibuloacral dysplasia [ 17 ] and Hutchinson-Gilford progeria [ 18 ] . The phenotypic spectrum from DCM to EDMD and limb girdle muscular dystrophy appears continuous.

  • Should I put feminist principles aside and do my familial duty because it's the nicer thing to do, or should I leave it to the men to wise up?

  • In addition to families with CFEOM1, we have identified several less common familial CFEOM phenotypes (CFEOM2 and CFEOM3).


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