Words similar to fabry
Example sentences for: fabry
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However, the more generalized cerebrovascular response noted in both the carotid and vertebro-basilar circulation suggests stimulus spread in Fabry disease, possibly due to a decreased response threshold in non-visual cortex vasculature.
Visual stimulation was chosen in particular because of the known predilection of the cerebrovascular abnormalities in Fabry disease for the posterior circulation [ 7 10 ] . The lack of an increase or decrease in visual rCBF reactivity in Fabry disease suggests normal neuro-vascular coupling mechanism [ 18 19 ] .
No difference in the global vasomotor reserve was found between Fabry patients and controls before or following ERT.
Acetazolamide, on the other hand, was hypothesized to identify areas of decreased cerebral perfusion following maximal cerebral vasodilation in Fabry disease compared to controls.
We hypothesized that the cerebral vasculopathy of Fabry disease is associated with abnormal cerebrovascular responses, and furthermore, that these would normalize with repeated intra-vascular infusion of α-galactosidase A [ 5 6 ] . We compared the functional cerebrovascular responses in Fabry disease to those in age and sex matched controls using both visual stimulation and acetazolamide challenge by [ 15O]H 2 O and positron emission tomography (PET) to measure rCBF.