Words similar to explants
Example sentences for: explants
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defining the NF-κB-inhibited explants.
Caspase 1 activates Caspase 3 and appears to promote production of the cytokine IL-1β, which upregulates the transcription of both Caspases 1 and 3, additionally potentiating apoptosis [ 37 38 ] . Thus, this regulatory mechanism of caspase gene expression would likely be diminished in SN50-treated explants were they allowed to develop further in culture.
Thus, we cultured E15 control, SN50-treated, and mSN50-treated explants in the presence of TNF (rTNF, 10 U/ml) supplementation for 4 or more days.
After 2 days in culture, SN50-treated explants exhibit a substantial decrease in gland size and branching morphogenesis compared to controls (compare Fig.
For cDNA expression and proteomic studies, E15 + 2 explants were collected, pooled, and stored at -70°C.
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