Words similar to exerts
Example sentences for: exerts
How can you use “exerts” in a sentence? Here are some example sentences to help you improve your vocabulary:
Therefore it is unlikely that Gleevec exerts the effect, if any, through c-kit on non-small cell lung cancer.
These data provide additional evidence that 4-AP exerts neither an anti-proliferative nor a pro-apoptotic influence on serum-supplemented GC cultures, because PCNA expression is a sensitive marker of GC proliferation and apoptosis [ 18 26 27 ] . The lack of 4-AP effect on GC viability is also evident from the flow cytometric analysis; the percentages of cells staining positive for propidium iodide were 8 ± 2% and 7 ± 2% in the presence and absence of drug (n = 4 samples of 10,000 cells/each from 4 GC isolations).
Recent results suggest that the C-terminal helix 12 of RXR exerts allosteric effects on RAR function [ 6 ] . However, additional studies suggest that corepressor binding to the apo-RAR component of the heterodimer blocks rexinoid induced binding of coactivators to RXR [ 7 ] . These results suggest that the mechanisms that account for the lack of responsiveness of the non-permissive complexes are complex.
However, the modern era of genomics has been accompanied by increasingly numerous claims that LGT is frequent [ 3, 4, 5, 6], and there now seems little doubt that LGT exerts a significant influence upon evolutionary histories.
Androgen exerts its biologic effects by binding to and activation of androgen receptor (AR) that trans-activates target genes through androgen responsive element (ARE) in the promoter of target genes [ 15 ] . In human breast cancer cells the effectiveness of retinoids in cell growth suppression was dictated by the presence of RAR [ 16 ] . Estrogen regulation of the expression of RAR α was mediated by interactions between estrogen receptor (ER) and estrogen responsive element (ERE) in the promoter of RAR α gene [ 17 ] . Because the DNA binding domains of steroid receptors including AR and ER are highly homologous, we postulated that similar mechanisms might also mediate the effect of androgen on RAR genes in prostate cells.
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