Words similar to exerts
Example sentences for: exerts
How can you use “exerts” in a sentence? Here are some example sentences to help you improve your vocabulary:
Androgen exerts its biologic effects by binding to and activation of androgen receptor (AR) that trans-activates target genes through androgen responsive element (ARE) in the promoter of target genes [ 15 ] . In human breast cancer cells the effectiveness of retinoids in cell growth suppression was dictated by the presence of RAR [ 16 ] . Estrogen regulation of the expression of RAR α was mediated by interactions between estrogen receptor (ER) and estrogen responsive element (ERE) in the promoter of RAR α gene [ 17 ] . Because the DNA binding domains of steroid receptors including AR and ER are highly homologous, we postulated that similar mechanisms might also mediate the effect of androgen on RAR genes in prostate cells.
Analysis of the genes identified as affected by IL-2 administration suggested that IL-2 exerts its effect at the target site by causing activation of monocytes.
Binding of mature TGFβ 1 to α V β 6 integrin exerts several downstream effects in TGFβ 1 -sensitive cells (Figure 9).
Since the Hh receptor, Ptc, serves to inhibit signaling, a small-molecule pathway activator would need to be capable of one of the following: first, interfering with the inhibitory effect that Ptc exerts on Smo; second, activating Smo without affecting Ptc; or third, activating the pathway downstream of Smo.
Since it has been reported that Gleevec can inhibit the function of PDGFR under the cell culture conditions, it is likely that Gleevec exerts its inhibitory effects on A549 lung cancer cells through inhibiting the PDGFR function.
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