Words similar to eus
Example sentences for: eus
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Both neuroleptics decreased the EMG during phase 2, where high frequency oscillations occur in the bladder pressure along with bursting in the EUS, with the highest dose of olanzapine (1.
Phase 3 of the EUS EMG (recorded during the falling phase of a bladder contraction) was not affected by clozapine administered intrathecally (Fig 6C).
Finally, the amplitude of the bursts observed during phase 2 in the EUS EMG were decreased to 32 ± 20.
In cats, serotonin antagonists caused a decrease in bladder capacity [ 43 ] however in anesthetized rats, serotonin antagonism did not have an effect on micturition [ 44 ] . Recently, a selective 5-HT1A receptor antagonist (WAY-100635) was reported to inhibit bladder contractions in rats [ 45 ] yet another report only observed an increase in the pressure threshold [ 46 ] . Olanzapine and risperidone have only low to modest affinity for the 5-HT1A receptor, and higher affinities for the 5-HT2A and 5-HT2C receptors [ 11 12 ] . Serotonin 5-HT2 and 5-HT3 receptors facilitate pudendal reflexes in the cat [ 47 48 ] , therefore it is possible that antagonism of these receptors may block the EUS in the anesthetized rat.
To date, only one case report of urinary incontinence with olanzapine therapy that resolved with ephredrine was found in the literature [ 14 ] . In the present study, olanzapine had more profound effects on urodynamic parameters and the EUS than risperidone and therefore the incidence of urinary disturbances in clinical practice would be predicted to be higher.
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