Example sentences for: estradiol

How can you use “estradiol” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • 4, 135 mM NaCI, 4.5 mM KCL, 1.5 mM CaCl 2 , 0.5 mM MgCL 2 , 1.0 mM NaH 2 PO4, 5.6 mM glucose, 0.3% BSA, and 10 -9M estradiol) containing 5 μCi of [ 3H]-myoinositol/ml of medium.

  • However, such a mechanism seems unlikely to account for the ability of estradiol to oppose the inhibitory effects of 4-AP on GC progesterone production.

  • Several active research programs are investigating the risk associated with serum estrogens, gonadotropins and urinary sex hormone metabolites for a variety of diseases including breast cancer [ 1 ] , endometrial cancer [ 2 ] , and osteoporosis [ 3 ] . The results of the few published studies suggest that the natural temporal variability (true variation over time, not variation due to storage or other factors) of some serum estrogens, gonadotropins and urinary sex hormone metabolites is sufficiently great that a single measurement occasion may be inadequate to ensure a reliable estimate [ 4 5 6 ] . Published intraclass correlation coefficients (ICC) vary between 0.06 and 0.62 for estradiol (E 2 ) and between 0.52 and 0.69 for estrone (E 1 ) [ 4 ] . Only the percent of free E 2 and of SHBG-bound E 2 have been found to be sufficiently reliable to account for as much as 50% of the variance in the true mean ( ICC > 0.7).

  • Estradiol has been shown to modulate IL-1 action on human osteoclasts in vitro; estrogen administration inhibited IL-1-mediated cytokine (IL-8) mRNA induction and caused increased Ocl apoptosis [ 26].

  • In this regard, ERβ differs from ERα, which probably binds ID motifs in a SERM-dependent fashion [ 49 50 ] and shows reduced binding to N-CoR in the presence of estradiol [ 39 ] . ERβ also differs from many other NRs, which either bind N-CoR in the absence of ligand and are released in the presence of ligand or interact with N-CoR in the presence of antagonists but not agonists [ 4 ] .


How many words do you know? Try our free vocabulary size test!


Search

Search for example sentences

Loading Loading...
Quantcast