Example sentences for: estradiol

How can you use “estradiol” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • To evaluate the relevance of the experimental results obtained using PGC-2, we examined the effect of 4-AP on the progesterone output of primary GC cultures supplemented with either the membrane permeable cAMP analog, 8-(4-chlorophenylthio) adenosine-3',5'-cyclic monophosphorothioate (8-CPT-cAMP, 1 mM) or estradiol 17β (500 ng/ml).

  • Plasma estradiol concentrations were low (< 15 pg/ml) in most females.

  • Thereby, the combined results of experiments performed using PGC-2 and primary GC cultures suggest that 4-AP-inhibition of GC progesterone production may be linked to decreased expression of StAR, decreased generation of cAMP, and decreased output of estradiol.

  • Phytoestrogens are plant compounds that are structurally and functionally similar to estradiol and have the ability to selectively bind estrogen receptors (estrogen receptor β greater than estrogen receptor α; [ 25 ] ). Phytoestrogens have received increased investigative attention due to their potential protective effects against age-related diseases (e.g.

  • Several active research programs are investigating the risk associated with serum estrogens, gonadotropins and urinary sex hormone metabolites for a variety of diseases including breast cancer [ 1 ] , endometrial cancer [ 2 ] , and osteoporosis [ 3 ] . The results of the few published studies suggest that the natural temporal variability (true variation over time, not variation due to storage or other factors) of some serum estrogens, gonadotropins and urinary sex hormone metabolites is sufficiently great that a single measurement occasion may be inadequate to ensure a reliable estimate [ 4 5 6 ] . Published intraclass correlation coefficients (ICC) vary between 0.06 and 0.62 for estradiol (E 2 ) and between 0.52 and 0.69 for estrone (E 1 ) [ 4 ] . Only the percent of free E 2 and of SHBG-bound E 2 have been found to be sufficiently reliable to account for as much as 50% of the variance in the true mean ( ICC > 0.7).


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