Example sentences for: essentiality

How can you use “essentiality” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Previous genetic analyses establishing the essentiality of cap formation were performed in the budding yeast S. cerevisiae.

  • Although recombinant Pct1 and Pce1 enzymes have been purified and characterized biochemically, and shown to function in cap formation when expressed in S. cerevisiae [ 12 20 21 ] , there have been no antecedent genetic studies of the essentiality of Pct1 or Pce1 in fission yeast.

  • Tests of gene essentiality in Candida necessitate serial disruption of both alleles using two different selection markers.

  • Here we have shown that the RNA triphosphatases Pct1 and CaCet1 are essential for viability of S. pombe and C. albicans, respectively The conclusion that CaCet1 is essential is based on a finding that none of the 54 independent isolates in the single-transformation test were homozygous for cacet1Δ; our interpretation is consistent with criteria established by Mitchell and colleagues for inference of essentiality using this genetic approach.

  • It is not a foregone conclusion that essentiality or dispensability of a gene product in S. cerevisiae can be extrapolated to pathogenic fungi.


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