Words similar to ese-

Example sentences for: ese-

How can you use “ese-” in a sentence? Here are some example sentences to help you improve your vocabulary:

However, TGFβ downregulated Ese-1/Esx mRNA levels faster than it upregulated Smad7 expression excluding the possibility that Smad7 mediates the TGFβ effect on Ese-1/Esx, at least at the initial phase.
Furthermore, we show for the first time that, in breast cancer cells, the Ese-1/Esx mRNA is downregulated by TGFβ.
One way by which Smad7 can inhibit TGFβ-dependent gene expression is by blocking phosphorylation, and, hence, nuclear import of Smad3 and Smad2 [ 23 ] . More recent data showing that Smad7 is able to interact with histone deacetylases suggest an additional role for Smad7 as a transcriptional co-repressor [ 50 ] . Thus, Smad7 might interfere directly with Ese-1/Esx gene transcription.
The other ets gene that we tested was ese-1/esx , a recently characterized member of the ets gene family, originally identified in epithelial cells [ 30 ] . Ese-1/Esx has been found to regulate the expression of TGFβ type II receptor [ 31 ] . We could show for the first time that the level of the Ese-1/Esx transcript was strongly downregulated in the presence of TGFβ.
It is remarkable that a constitutively active form of JNK activator MKK and Smad7 are able to cooperatively downregulate TGFβ-responsive promoters [ 53 ] . It is quite possible that a Smad7/JNK synergistic interaction is involved in the TGFβ-dependent downregulation of Ese-1/Esx expression, where JNK alone might mediate the initiation of the TGFβ-induced repression.