Example sentences for: ese-

How can you use “ese-” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The other ets gene that we tested was ese-1/esx , a recently characterized member of the ets gene family, originally identified in epithelial cells [ 30 ] . Ese-1/Esx has been found to regulate the expression of TGFβ type II receptor [ 31 ] . We could show for the first time that the level of the Ese-1/Esx transcript was strongly downregulated in the presence of TGFβ.

  • However, TGFβ downregulated Ese-1/Esx mRNA levels faster than it upregulated Smad7 expression excluding the possibility that Smad7 mediates the TGFβ effect on Ese-1/Esx, at least at the initial phase.

  • We present data showing that TGFβ downregulated the Ese-1/Esx transcript, a novel and yet unpublished finding.

  • It is remarkable that a constitutively active form of JNK activator MKK and Smad7 are able to cooperatively downregulate TGFβ-responsive promoters [ 53 ] . It is quite possible that a Smad7/JNK synergistic interaction is involved in the TGFβ-dependent downregulation of Ese-1/Esx expression, where JNK alone might mediate the initiation of the TGFβ-induced repression.

  • It is possible that TGFβ does not require Smad3/4 or p38 to inhibit Ese-1/Esx-expression.


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