Words similar to erlotinib

Example sentences for: erlotinib

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T790M in the context of either transiently expressed wild-type EGFR or the mutant alleles del L474–E749;A750P or L858R impairs inhibition by gefitinib or erlotinib as assessed by autophosphorylation.
The analysis presented here includes specimens we previously reported on ( n = 17 for gefitinib and n = 17 for erlotinib) [3].
In three additional patients (case histories not described here) with lung adenocarcinomas who improved but subsequently progressed on therapy with either gefitinib or erlotinib, we examined DNA from tumor specimens obtained during disease progression.
In addition, only half of this small cohort of patients with NSCLC with clinical resistance to gefitinib or erlotinib had the T790M substitution.
Similar results were obtained using erlotinib against wild-type and del E747–L747;A750P EGFRs in comparison to the corresponding mutants containing the T790M mutation (Figure 4C).