Example sentences for: erks

How can you use “erks” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • These results suggest that DSLET utilizes a G i -coupled δ-OR to stimulate ERK 1 and 2. We then took advantage of the HEK-293 cell line's endogenous expression of the EGFR to examine this receptor's ability to activate ERKs.

  • Of interest to these studies are the three subfamilies within the mitogen-activated protein kinase (MAPK) superfamily including the extracellular signal-related kinases (ERKs), p38 and c-jun N-terminal kinases (JNKs) [ 31 ] . TNFα is one of many cytokines involved in luteal regression.

  • The levels of phospho-ERKs increased within 5 min of TNFα treatment, peaked by 10 min and decreased by 30 min (Fig.

  • In EGF pre-treated cultures, acute EGF (10 ng/ml) was unable to increase the expression of phospho-ERKs compared to media-exposed controls (Figure 6).

  • The mutation of one of the tyrosines (Y318F) in the δ-OR or the presence of the Src inhibitor, PP1, significantly reduces tyrosine phosphorylation of this receptor and its ability to activate ERKs [ 11 13 ] . However, a small degree of δ-OR agonist-mediated ERK activation remained in cells expressing the Y318F mutant receptor, suggesting that a second mechanism or an additional tyrosine could be involved.


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