Words similar to er-
Example sentences for: er-
How can you use “er-” in a sentence? Here are some example sentences to help you improve your vocabulary:
nmt55/p54 nrbtranscripts were detected at varying levels in both ER+ and ER- tumors.
The βRARE-TK-Luc reporter plasmid with three copies of the DR-5 motif from the promoter of the mouse RARβ2 gene has been described previously, as has the CYP2B10-TK-Luc reporter with two copies of the DR-4 type elements from the promoter of the mouse CYP2B10 gene and the CYP3A4-TK-luc reporter with three copies of the ER-6 element from the human CYP3A4 promoter [ 16 ] . Expression vectors for full length mCAR and RXR proteins were as described [ 9 ] . The cdm8-mCARΔ8 deletion construct containing a deletion of the last 8 amino acids and the mutant with 2 helix 3 mutations (F171L, I174A) that block ligand binding and response have been described previously [ 16 ] , as has the cdm8-RXRΔ19 construct with a deletion of the last 19 amino acids [ 3 ] .
Results from Western blot analyses with polyclonal antibodies NMT-4 and NMT-5 showed that nmt55/p54 nrbexpression was absent, or greatly reduced, in most of ER- tumors.
We have previously shown that nmt55/p54 nrbprotein was expressed in most ER+/PR+ human breast tumors but was undetectable in ER-/PR- human breast tumors [ 13 ] . Since loss of hERα expression is associated with poor prognosis and continued expression of hERα is associated with disease-free survival and correlates well with tumor differentiation state, we wanted to investigate the regulation of nmt55/p54 nrbexpression.
The opioid agonist, [D-Ser-Leu-enkephalin-Thr (DSLET), was received from the National Institute of Drug Abuse (NIDA, Baltimore, MD) and the antagonist, naltrindole, was purchased from Research Biochemicals, Inc., (Natick, MA).
Loading...