Example sentences for: er-

How can you use “er-” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • No antibodies detected nmt55/p54 nrbprotein in ER- human breast tumors (lanes 1-5) confirming previous observations [ 13 ] . Monoclonal antibody NMT-1 and polyclonal antibody NMT-5 detect nmt55/p54 nrbprotein in all ER+ tumor samples (lanes 5-10), albeit at varying levels.

  • Roughly 40% (14/36) of the top characterized genes associated with this group encode protein-folding chaperones localized to different subcellular regions (including those that encode the cytosolic Hsp90 and Hsp70 factors, the mitochondrial Hsp10/Hsp60p and Ssc1p, and the ER- and mitochondrial-associated Ssa1p), and their induction following heat shock and diamide treatment is likely to be in response to widespread protein unfolding inflicted by these conditions.

  • Results from Western blot analyses with polyclonal antibodies NMT-4 and NMT-5 showed that nmt55/p54 nrbexpression was absent, or greatly reduced, in most of ER- tumors.

  • Since there was no apparent nmt55/p54 nrbmRNA regulation in ER+ or ER- human breast tumors, it was possible that monoclonal antibody NMT-1 may not detect the presence of potential multiple isoforms of nmt55/p54 nrbprotein especially in ER- tumors.

  • In this study, we compared mRNA levels in ER+ and ER- human breast tumors using Northern blot analysis and ribonuclease protection assay to assess if nmt55/p54 nrbis regulated at the transcription level.


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