Words similar to er-
Example sentences for: er-
How can you use “er-” in a sentence? Here are some example sentences to help you improve your vocabulary:
No antibodies detected nmt55/p54 nrbprotein in ER- human breast tumors (lanes 1-5) confirming previous observations [ 13 ] . Monoclonal antibody NMT-1 and polyclonal antibody NMT-5 detect nmt55/p54 nrbprotein in all ER+ tumor samples (lanes 5-10), albeit at varying levels.
Roughly 40% (14/36) of the top characterized genes associated with this group encode protein-folding chaperones localized to different subcellular regions (including those that encode the cytosolic Hsp90 and Hsp70 factors, the mitochondrial Hsp10/Hsp60p and Ssc1p, and the ER- and mitochondrial-associated Ssa1p), and their induction following heat shock and diamide treatment is likely to be in response to widespread protein unfolding inflicted by these conditions.
Results from Western blot analyses with polyclonal antibodies NMT-4 and NMT-5 showed that nmt55/p54 nrbexpression was absent, or greatly reduced, in most of ER- tumors.
Since there was no apparent nmt55/p54 nrbmRNA regulation in ER+ or ER- human breast tumors, it was possible that monoclonal antibody NMT-1 may not detect the presence of potential multiple isoforms of nmt55/p54 nrbprotein especially in ER- tumors.
In this study, we compared mRNA levels in ER+ and ER- human breast tumors using Northern blot analysis and ribonuclease protection assay to assess if nmt55/p54 nrbis regulated at the transcription level.