Words similar to env
Example sentences for: env
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However, the major env components were never N-terminally sequenced and the data could also be interpreted to be the result of the removal of about 12 kda from the N-termini of these proteins at the cleavage site shown in Fig.
The upper limit of normal for serum β 2 microglobulin for healthy HIV-seronegative Ugandan adults is 3.5 mg/L [ 18 ] . HIV-infection was determined by HIV-1 EIA (Recombigen HIV-1 env + gag EIA; Cambridge Bioscience, Worcester, Massachusetts, USA).
In CD8 +T cells from African HIV +patients, stimulated with env peptide, both IFN-γ and TNF-α production were increased over controls [ 52 ] . PBMC from the elderly (almost healthy donors) showed upregulation of TNF-α in unstimulated cultures [ 52 ] . HLA-DR activation of CD8 +CD57 +cells from elderly subjects strongly produced TNF-α [ 48 ] . Lipopolysaccharide-activation of T cells from aged donors induced higher levels of TNF-α than controls in two separate studies [ 53 31 ] . Finally, in HIV +patients receiving HIV type 1 antigen, both INF-γ and TNF-α were significantly increased in memory T cells activated by antigen [ 54 ] .
Virus-specific CD8+ T-cells were quantitated in the blood of both animals at days 0, 4, and 12 postinfection using 3 tetrameric Mamu-A*01 molecules complexed with the SIV mac Gag 181, Env 622, and Tat 28 peptides (T.M.
Overall, the size of the virus-specific CD8+ T-cell response in the blood was higher in animal 817 and, interestingly, a large population of Tat-specific CD8+ T-cells appeared in the blood as early as day 4, whereas in the same animal CD8+ T-cells specific to Gag 181 and Env 622 peaked later (Fig.
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