Example sentences for: env

How can you use “env” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Blood, lymph nodes, and lamina propria lymphocytes were cultured in vitro in the presence of IL-2 and the virus-specific Gag 181, Tat 28, and Env 622 peptides to assess the ability of the tetramer-positive CD8+ T-cell population to expand upon antigen stimulation.

  • Quantitation of the ex vivo CD8+ T-cell population specific for Gag, Tat, and Env in the systemic tissues of both animals revealed that, in contrast to the blood, the highest virus-specific CD8+ T-cell response was found in most tissues of animal 819, challenged by the intravenous route (Figs.

  • In the same animal, a higher number of tetramer-specific CD8+ T-cells able to proliferate in response to all epitopes tested (Gag 181, Tat 28, and Env 622) was found in jejunum lamina propria than in other tissues.

  • In CD8 +T cells from African HIV +patients, stimulated with env peptide, both IFN-γ and TNF-α production were increased over controls [ 52 ] . PBMC from the elderly (almost healthy donors) showed upregulation of TNF-α in unstimulated cultures [ 52 ] . HLA-DR activation of CD8 +CD57 +cells from elderly subjects strongly produced TNF-α [ 48 ] . Lipopolysaccharide-activation of T cells from aged donors induced higher levels of TNF-α than controls in two separate studies [ 53 31 ] . Finally, in HIV +patients receiving HIV type 1 antigen, both INF-γ and TNF-α were significantly increased in memory T cells activated by antigen [ 54 ] .

  • The upper limit of normal for serum β 2 microglobulin for healthy HIV-seronegative Ugandan adults is 3.5 mg/L [ 18 ] . HIV-infection was determined by HIV-1 EIA (Recombigen HIV-1 env + gag EIA; Cambridge Bioscience, Worcester, Massachusetts, USA).


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