Words similar to enrichment
Example sentences for: enrichment
How can you use “enrichment” in a sentence? Here are some example sentences to help you improve your vocabulary:
This group of 30 genes contained eight ergosterol biosynthesis genes; this proportion represented an enrichment compared to the rest of the genome (hypergeometric p -value < 6 × 10 -6after Bonferroni correction for multiple testing).
We suggest that the enrichment of MHCK-A to polar ruffles of dividing cells may represent a mechanism by which D. discoideum cells locally disassemble myosin II filaments to facilitate the polarized recruitment of filaments to the forming contractile ring/furrow zone.
Studies of the phenotype of CD8 +T cells in the synovial membrane and fluid may shed light as to whether this skewed phenotype is also found in these sites or whether there is an enrichment for CD45RA +CD62L -CD8 +T cells, indicating increased recruitment into the inflamed synovium in RA.
This model is consistent with the recent report that MHCK-A displays enrichment into anterior F-actin-rich protrusions of polarized cells during chemotaxis, and into phagocytic and macropinocytotic extensions [ 23 ] . The polar localization of MHCK-A would be consistent with the long-standing "polar relaxation" model for cytoskeletal reorganization during cytokinesis [ 33 ] . MHCK-A may represent a factor that contributes to polar relaxation in this system via polar disassembly of myosin II filaments.
To enrich for clones with increased survival in human macrophages, the library was passed through THP-1 macrophages as shown schematically in Figure 1. THP-1 is a human monocyte-derived macrophage cell line [ 21 ] and wild-type M. smegmatis bacteria are rapidly killed by THP-1 macrophages [ 22 ] . After three rounds of enrichment, the resulting clones were analyzed individually by Southern blot to evaluate the number of different clones present as previously described [ 20 ] . Out of the 3000 colonies recovered, genomic DNAs from the bacteria of 90 randomly chosen colonies were digested with Pst I and hybridized with the pYUB178 vector.
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