Words similar to endoplasmic
Example sentences for: endoplasmic
How can you use “endoplasmic” in a sentence? Here are some example sentences to help you improve your vocabulary:
For direct testing, temperature sensitive mutants in genes involved in vesicular budding from the endoplasmic reticulum were obtained from others and crossed to all mutants isolated in the screen.
For instance, HIV-1 infection is able to down-regulate major histocompatibility complex type I (MHC-I) by various different viral proteins, including Tat which represses the transcription of MHC-I, Vpu which retains nascent MHC-I chains in the endoplasmic reticulum, and Nef which can mediate selective internalization of MHC-I molecules from the plasma membrane.
The Rat Genome U34 array was found to contain probe-sets representing the ER chaperones glucose-regulated protein (GRP) 78, protein disulfide isomerase, GRP94, calreticulin and endoplasmic reticulum protein 29 (EPR29), GADD153 and PERK.
The resulting enzyme is both mislocalized and unstable [ 27 ] . Another mutation, Q1098P, was found to cause retention of SI in the transport pathway between the endoplasmic reticulum and Golgi apparatus [ 28 ] . An unusual mutation, Q117R, that alters the structure close to the O-glycosylated stalk domain, leads to random distribution of the enzyme to both the apical and basolateral cell membranes [ 29 ] . An unusual human mutation that causes SI to be secreted rather than retained in the plasma membrane demonstrates that the enzyme is required to be at the enterocyte cell surface [ 30 ] .
In contrast, sα i2 was not detected at plasma membranes, but instead typically displayed an intracellular and perinuclear staining pattern (Figure 2Band 2D), consistent with localization to intracellular membranes as previously described [ 3 4 ] . The subcellular localization of sα i2 showed overlap in immunofluorescent staining with the Golgi protein, β-COP (Figure 3Aand 3B) and the endoplasmic reticulum protein PDI (Figure 3Cand 3D); localization of sα i2 exclusively to Golgi was not observed, even at the lowest levels of detection.
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