Example sentences for: endoplasmic

How can you use “endoplasmic” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Secreted proteins, like all other proteins, are synthesized in the endoplasmic reticulum (ER) and are specifically packaged into vesicles that bud off from the ER in a GTP-dependent process [ 3, 4].

  • For direct testing, temperature sensitive mutants in genes involved in vesicular budding from the endoplasmic reticulum were obtained from others and crossed to all mutants isolated in the screen.

  • Two highly conserved responses are observed under conditions of endoplasmic reticulum (ER) stress; the ER overload and unfolded protein responses [ 24 25 ] . The unfolded protein response is characterized by generalized suppression of protein synthesis and the specific induction of ER-resident proteins and GADD153 [ 24 ] . The transcription factor nuclear factor kB is activated during the ER overload response, leading to the downstream induction of pro-inflammatory proteins [ 25 ] . Therefore, the transcriptional modulation of GADD153 and IkB by mefloquine suggests that the ER might be a target of the drug.

  • This set of genes includes several with roles in membrane budding, vesicular formation, and membrane fusion, and translocation of proteins across the membrane of the endoplasmic reticulum.

  • Molecular chaperones bind to nascent proteins in the endoplasmic reticulum (ER), promote proper protein folding, and prevent the aggregation of nonnative and misfolded proteins.


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