Words similar to endocrine
Example sentences for: endocrine
How can you use “endocrine” in a sentence? Here are some example sentences to help you improve your vocabulary:
Human estrogen receptor alpha (hERα) is detected in 50-85% of all breast tumors [ 6 ] , and is utilized as a prognostic marker to identify patients who may have a favorable response to hormonal or endocrine manipulations.
Endocrine therapy with the antioestrogen tamoxifen can mediate the downregulation of c- myc , culminating in cell cycle arrest [ 44 ] . Berns et al . [ 12 ] reported that 38% of patients with amplification of c- myc or with coamplification of c- myc and HER-2 / neu profited from endocrine therapy.
Overall, these data are consistent with previous reports that endocrine cells express voltage-sensitive ion channels that can contribute to the regulation of not only resting membrane potential and cell volume, but also cell proliferation and steroidogenesis [ 12 13 16 18 21 28 29 30 31 32 33 34 35 36 37 ] . The K +currents blocked by 4-AP in pig GC are conducted by ion channels formed by heteromeric complexes of pore-forming subunits from the KCNA (also called Kv1 or Shaker) family of proteins and accessory subunits from the KCNAB (also called Kvβ) family of proteins [ 4 ] . Similar 4-AP-sensitive K +currents play a key role in transduction of mitogenic signals in a variety of cell types, and 4-AP treatment has been associated with not only growth arrest but also apoptosis [ 2 3 8 9 10 14 38 39 40 41 42 ] .
Although the biological mechanisms underlying the inverse association between menarcheal age and adult obesity are uncertain, it has been suggested that early maturing girls may have a longer period of positive energy balance [ 1 ] , or that various endocrine factors influence both the rate of sexual maturation and the accumulation of body fat [ 6 ] . However, it is also possible that the apparent influence of menarcheal age on adult obesity reflects the underlying importance of childhood obesity, with relatively fat children at increased risk for both early menarche [ 7 9 13 14 15 ] and adult obesity [ 7 16 ] .
In this regard, endocrine disrupters are environmental chemicals that mimic or modulate the physiological effects of steroid hormones, especially that of estrogens [ 23 24 ] . Of all of the considered estrogenic endocrine disrupters examined thus far, phytoestrogens have been extensively studied [ 23 24 ] (however, little research has been conducted examining VSM in relationship to phytoestrogens).
Loading...