Example sentences for: encapsidated

How can you use “encapsidated” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The hepadnaviral P protein possesses many unique features relative to the better studied reverse transcriptases of the retroviruses: (i) it uses its own amino-terminal domain as a protein primer for initiation of DNA synthesis [ 7, 9, 10], (ii) it cannot be isolated in an active form from virions without partial proteolysis or denaturation [ 13, 14, 15], and (iii) under normal circumstances it is active only on the endogenous pregenomic RNA that is encapsidated with it in the viral cores [ 16].

  • As mentioned before, the N-encapsidated genome-length RNAs are indeed extremely resistant to nucleases, to the extent that formation of such nuclease-resistant RNA products is in fact considered a defining criterion for viral replication in vitro and in vivo [ 32 ] . While the resistance of the viral genomic RNA to dsRNA has important ramifications for antiviral therapy, it is also clear that the dsRNA approach cannot be used against cis -acting NNR viral genomic sequences such as the intergenic regions, for which the cDNA-based approach will continue to be the method of choice [ 16 ] . It is obvious that a creative combination of the two techniques will lead to exciting possibilities in the reverse genetics of RNA viruses and in the antiviral regimen.

  • 2. A substantial fraction of mutant genomes should be encapsidated with wild-type protein.

  • It has a non-segmented, positive strand genome of approximately 8.5 Kb encapsidated by viral proteins, VP1, VP2, VP3 and VP4.

  • 3. The ratio of mutant genomes encapsidated in wild-type protein to wild-type genomes encapsidated in mutant protein should decrease with increasing m.o.i.


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