Example sentences for: encapsidated

How can you use “encapsidated” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • 3. The ratio of mutant genomes encapsidated in wild-type protein to wild-type genomes encapsidated in mutant protein should decrease with increasing m.o.i.

  • There will typically be several orders of magnitude more mutant genomes encapsidated in wild-type protein than wild-type genomes encapsidated in mutant protein.

  • , when a mutant offspring is encapsidated by its parent's proteins.

  • The availability of large quantities of N protein then allows encapsidation of nascent leader RNA by N. This leads to the switching of the RdRP to the "replication mode", resulting in the synthesis of full-length, encapsidated anti-genomic RNA, which is in turn replicated into more genomic RNA [ 15 ] . Thus, the very requirement of N for replication ensures that all full-length genomic and antigenomic RNA are wrapped with N protein, i.e., encapsidated [ 15 ] . The new pool of replicated genomic RNA serves as templates for secondary transcription.

  • As mentioned before, the N-encapsidated genome-length RNAs are indeed extremely resistant to nucleases, to the extent that formation of such nuclease-resistant RNA products is in fact considered a defining criterion for viral replication in vitro and in vivo [ 32 ] . While the resistance of the viral genomic RNA to dsRNA has important ramifications for antiviral therapy, it is also clear that the dsRNA approach cannot be used against cis -acting NNR viral genomic sequences such as the intergenic regions, for which the cDNA-based approach will continue to be the method of choice [ 16 ] . It is obvious that a creative combination of the two techniques will lead to exciting possibilities in the reverse genetics of RNA viruses and in the antiviral regimen.


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