Words similar to emd

Example sentences for: emd

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In these studies EMD 57033 resulted in only small increases in myocardial oxygen consumption and this was felt related to the ability of EMD 57033 to increase inotropy without increasing calcium cycling (though intracellular calcium was not directly measured).
During positive inotropy there is an increase in ATP utilization and thus myocardial oxygen consumption related to increased cross-bridge cycling and calcium handling [ 1 ] . Heat measurements of isolated heart muscle have assigned approximately 50% of total energy consumption to cross-bridge cycling and 20% to calcium cycling [ 2 ] . However, recently, studies in both isolated hearts and myocytes [ 3 4 ] , examining the energetic effects of increasing inotropy with the calcium sensitizing agent EMD 57033 have suggested that the energetic cost associated with increasing inotropy is largely related to calcium cycling.