Example sentences for: embryonal

How can you use “embryonal” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Human embryonal kidney (HEK) cells (line 293) and NIH 3T3 mouse fibroblasts were obtained from American Type Culture Collection (Rockville, MD) and were maintained at 37°C in a 5% CO 2 atmosphere in Dulbecco's modified Eagle's medium containing 10% (v/v) fetal bovine serum.

  • RA induces development of primitive endodermal cells from a subset of embryonal carcinoma cell lines, and is an endogenous signal that directs development of posterior organs like the pancreas from embryonic endoderm [27,28].

  • Sequences flanking the virus, isolated by inverse PCR, hybridized to a transcript of approximately 1.8 Kb, and were used to screen a PCC3 embryonal carcinoma cell cDNA library.

  • Medulloblastomas, embryonal neoplasms arising in the cerebellum, are the most common malignant pediatric brain tumor.

  • For example, mouse embryonal stem (ES) cells with homozygous deletion of the PTEN gene exhibit increased anchorage-independent growth as compared to normal ES cells [ 12 ] . Similarly, transfer of a wild type PTEN gene into anchorage-independent human glioblastoma cells (which lack functional PTEN), results in their greatly reduced ability to form colonies in soft agar [ 4 5 6 ] . The interpretation of these latter findings, however, is complicated by the strong anti-proliferative effects of PTEN even in monolayer culture, which is consistently observed when the wild type version of this gene is introduced into PTEN-negative tumor cells [ 4 6 7 8 9 10 18 33 ] . Moreover, in human glioma and breast cancer cell lines, the ectopic expression of wild type PTEN leads to anoikis, which is apoptosis initiated by the disruption of cell matrix-interactions [ 23 34 35 36 ] .


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