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Example sentences for: elovl

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An NCBI BLAST search identified the murine homologue of yeast ELO2 (Elovl2) to be Ssc2 (Sequence similarity to Cig30), predominating in liver and testes [ 62 ] ; complementation studies in yeast mutants indicated the functional equivalent of ELO3 (Elovl3) is Ssc1 [ 35 ] . Substrates of mouse Ssc2 were AA and EPA (DHA was not tested) [ 35 ] . Thus, FUNG and FISH feeding may transcriptionally regulate their subsequent conversion to elongated products.
The yeast gene Elo1 is associated with elongating FAs with 14 to 16 C; yet, this activity is often masked by cytosolic FA synthase activity [ 60 ] . Evidence shows Elovl2 elongates FA to 24C; and Elovl3 elongates FA to 26C, with preference for converting FA from 24C to 26C, in yeast [ 61 ] .
Several genes that may contain SRE promoters such as SREBP-1 and Acly, and Elovl2 and Cd36, were found in the same cluster.
The probe set for Elovl2 was down regulated, particularly with FISH and the combined diet (-1.
The elongase Elovl2 may contain an SRE, and therefore be under the transcriptional control of SREBP [ 35 ] ). Due to observations in the metabolite data, which suggests a repression of elongase activity, the dietary regulation of Elovl2 and Elovl3 was focused on.