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Example sentences for: elovl

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The yeast gene Elo1 is associated with elongating FAs with 14 to 16 C; yet, this activity is often masked by cytosolic FA synthase activity [ 60 ] . Evidence shows Elovl2 elongates FA to 24C; and Elovl3 elongates FA to 26C, with preference for converting FA from 24C to 26C, in yeast [ 61 ] .
8*), consistent with some of the lipid data described below; whereas the probe set for Elovl3 was not affected by FUNG, up regulated with FISH, and down regulated, although not significantly, with the combination diet (-1.
The elongase Elovl2 may contain an SRE, and therefore be under the transcriptional control of SREBP [ 35 ] ). Due to observations in the metabolite data, which suggests a repression of elongase activity, the dietary regulation of Elovl2 and Elovl3 was focused on.
An NCBI BLAST search identified the murine homologue of yeast ELO2 (Elovl2) to be Ssc2 (Sequence similarity to Cig30), predominating in liver and testes [ 62 ] ; complementation studies in yeast mutants indicated the functional equivalent of ELO3 (Elovl3) is Ssc1 [ 35 ] . Substrates of mouse Ssc2 were AA and EPA (DHA was not tested) [ 35 ] . Thus, FUNG and FISH feeding may transcriptionally regulate their subsequent conversion to elongated products.
The probe set for Elovl2 was down regulated, particularly with FISH and the combined diet (-1.