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Example sentences for: elevated

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Moreover, increasing the abundance of TRPC3 in cultured myotubes prolongs the period in which intracellular calcium is elevated following a depolarizing stimulus, sustains the transcription factor NFAT within the nucleus, and augments expression of NFAT-dependent target genes [40].
Indeed, elevated levels of ProCT peptides have been found to persist at least 24 h following an appropriate stimulus, in contradistinction to other markers, such as tumor necrosis fctor-α, whose levels may be only transiently elevated after an inflammatory challenge [ 34, 35].
However, Wnt signaling also promotes the expression of such genes as Cyclin D1 [ 22 ] and MYC [ 23 ] , which are not elevated by BMP.
In contrast to other models of obesity, however, diet-induced obesity was not associated with either elevated glucocorticoid levels or reduced hypothalamic POMC mRNA.
ER function is critical if protein synthesis and folding is to successfully occur in eukaryotic cells [ 11 12 ] . ER stress, induced by cellular events as diverse as disrupted calcium homeostasis, elevated levels of reactive oxygen species and viral infection, leads to accumulation of dysfunctional ER chaperones and misfolded proteins [ 11 ] . Cells respond by one or both of two conserved stress response pathways.