Example sentences for: efforts

How can you use “efforts” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Several efforts have been made to develop alternative, affordable CD4 counting methods for resource-poor settings.

  • One of the major cellular serine/threonine protein phosphatases is protein phosphatase type 1 (PP1) [ 1 ] . An abundant enzyme expressed in all cells, complex regulation of PP1 is thought to be essential for proper temporal and spatial regulation of PP1 catalytic activity towards individual substrates [ 2 ] . Three different isotypes of the catalytic subunit, designated PP1α, PP1δ, and PP1γ1, are expressed in many different cell types [ 3 ] . Studies employing many eukaryotic systems all point to a crucial role for PP1 activity in controlling cell cycle progression, and an absolute requirement of this activity for mitotic exit [ 4 5 6 7 ] . There is also evidence to suggest that phosphorylation of PP1 and its associated proteins by the cyclin-dependent kinases may regulate PP1 activity in a cell cycle stage-dependent manner [ 8 9 10 ] . Hence, current efforts are directed towards identification of cell cycle-dependent substrates for PP1, and how regulation of PP1 activity towards these substrates controls the cell division cycle.

  • Similar efforts have worked before in Brazil (1964-69), Chile (1973-1985), and Peru (1991-now).

  • Will the extension of ART to millions who suffer from AIDS in developing countries be the long-awaited breakthrough in the response to HIV, or will the emphasis on treatment detract from prevention efforts, and thus hamper AIDS control in the medium and long term?

  • Since it will not be possible to test many agents in large randomized clinical trials, efforts are underway to develop useful tissue-based surrogate end-point biomarkers that can be used to select only the most promising agents (and doses) for large-scale trials.


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