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Example sentences for: efflux
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Chloride channels or chloride ions are known to influence cAMP-stimulated steroidogenesis by adrenal cells [ 29 ] , human chorionic gonadotropin (hCG)-stimulated steroidogenesis by amphibian follicle-enclosed oocytes [ 56 ] , as well as LH-stimulated steroidogenesis in rat Leydig cells [ 29 ] , MA-10 cells [ 59 ] , and chicken GC [ 35 ] . In mammalian cells, removal of extracellular chloride stimulates basal and protein kinase A (PKA)-dependent steroid hormone production by increasing the expression of StAR and potentiating the effects of submaximal concentrations of cAMP [ 29 59 ] . The proposed mechanism of action involves chloride efflux, depolarization of the mitochondrial and plasma membranes, and alterations to protein synthesis and cholesterol transport [ 29 59 ] .
Moreover, the rates of decline in the amount of radiolabeled TCA associated with the cells after withdrawal of the radiolabeled bile acids from the culture medium was comparable among the different clones (Figure 9C), indicating that the rate of bile acid efflux from these cells was also not affected by the presence of HBAB.
Since TNFRSF induces cell death by causing an efflux of glutathione (GSH) in other cell types [ 42 ] we sought to determine if pretreatment of CLENDO cells with GSH would attenuate lethality associated with TNFα treatment.
The apparent efflux observed in CHO.asbt.
Normal mitochondrial iron homeostasis minimally depends on wild-type frataxin to control efflux.
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