Words similar to effectors
Example sentences for: effectors
How can you use “effectors” in a sentence? Here are some example sentences to help you improve your vocabulary:
That ERK2 is of very high relative importance is consistent with the observation that the MAPK/ERK overrides apoptotic signaling from Fas, TNF and TRAIL receptors [ 58 ] . It appears that effectors apart from the MAPK/ERK pathway may also mediate the anti-apoptotic function of c-Raf [55a].
GPCRs stimulate heterotrimeric G proteins which release activated Gα and Gβγ subunits to interact with a variety of effectors.
Signals are initiated by tyrosine phosphorylation of upstream effectors that recruit these adaptors to assemble larger protein complexes by bringing downstream effectors to the distinct cellular compartments for activation.
By examining a range of subspaces, this analysis can be used to partition a transcription profile and define which effectors are responsible for particular patterns of expression.
IL-1β, which was significantly upregulated in NHBEs following CSC exposure, has been shown to be important for activation of IL-8 [ 6 ] and ICAM-1 [ 4 ] . This is also consistent with the report that epithelial cells regulate inflammatory events by secreting cytokines and chemokines such as IL-1β, IL-8, GM-CSF, TNF-α, and sICAM-1 [ 2 ] . These paracrine effectors can then produce further primary local inflammation or amplify the effects of previously activated macrophages, eosinophils, mast cells, or lymphocytes.
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