Example sentences for: effectors

How can you use “effectors” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Mis-regulation of Wnt signaling leads to the development of several human cancers, including colon carcinomas and melanoma [ 1 ] . Canonical Wnt signaling initiates in the binding of a Wnt ligand to its cell surface receptor, members of the frizzled gene family, along with the co-receptor LRP5/6 [ 2 3 ] , leading to changes in the activities of cytoplasmic effectors resulting in the stabilization of beta-catenin protein.

  • It has also been suggested that circulating C-reactive protein levels may not reflect all relevant inflammatory effectors, owing to post-transcriptional regulation of C-reactive protein [22].

  • GPCRs stimulate heterotrimeric G proteins which release activated Gα and Gβγ subunits to interact with a variety of effectors.

  • The activation of Wnt signaling by various effectors in pPacPL was then determined by measurement of relative luciferase activity (Figure 1B).

  • The soluble messenger IP 3 binds to receptors located on calcium store membranes, causing release of calcium into the cytosol, while DAG remains in the membrane, where it can activate downstream effectors.


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