Example sentences for: effectors

How can you use “effectors” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Mutations in different effectors of Wnt signaling have been identified in a variety of cancers.

  • IL-1β, which was significantly upregulated in NHBEs following CSC exposure, has been shown to be important for activation of IL-8 [ 6 ] and ICAM-1 [ 4 ] . This is also consistent with the report that epithelial cells regulate inflammatory events by secreting cytokines and chemokines such as IL-1β, IL-8, GM-CSF, TNF-α, and sICAM-1 [ 2 ] . These paracrine effectors can then produce further primary local inflammation or amplify the effects of previously activated macrophages, eosinophils, mast cells, or lymphocytes.

  • Importantly, the expression of hCARΔcyt by T cells was stable and high-level at all stages of development, from double-negative thymocytes to Th1 and Th2 effectors.

  • Glucocorticoids (GC's) are the effectors of stress and necessarily impact multiple target tissues during normal function.

  • The Hh-signaling pathway comprises three main components: the Hh ligand; a transmembrane receptor circuit composed of the negative regulator Patched (Ptc) plus an activator, Smoothened (Smo); and finally a cytoplasmic complex that regulates the Cubitus interruptus (Ci) or Gli family of transcriptional effectors.


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