Words similar to effectors

Example sentences for: effectors

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We then focused our attention on two particularly important pathways relative to cell proliferation and apoptosis, ERK 1/2 and Caspase 3. Downstream of activated ERK 1/2 is an upregulation of cell proliferation proteins and potentially enhanced cell division, as well as a protective effect over apoptotic signaling via suppressed activation of caspase effectors.
, 1996 [ 3 ] ). For example, some classical neurotransmitters such as 5-HT have short-term effects on ion channels and other effectors such as adenylyl cyclase but also have growth factor-like effects in developing brain [ 4 ] and mitogenic effects on fibroblasts (reviewed in Gerhardt and van Heerikhuizen, 1997 [ 5 ] ). The peptide hormones insulin and IGF-1 have both short-term metabolic effects and long-term actions on cell growth and differentiation.
The pheromone response pathway is commonly depicted as a simple, linear transmission of the mating signal from the membrane receptor, Ste2p (for alpha-factor) or Ste3p (for a-factor), to the nuclear effectors, Ste12p and Mcm1p, via a MAPK cascade.
By examining a range of subspaces, this analysis can be used to partition a transcription profile and define which effectors are responsible for particular patterns of expression.
The former class of adaptor proteins form complexes with downstream effectors in a constitutive fashion via their SH3 domains.