Words similar to effectors

Example sentences for: effectors

How can you use “effectors” in a sentence? Here are some example sentences to help you improve your vocabulary:

Activation of ROCK1 occurs when a Rho protein binds to the Rho-binding domain, causing a conformational change that opens the kinase domain for the phosphorylation of downstream effectors [23].
The pheromone response pathway is commonly depicted as a simple, linear transmission of the mating signal from the membrane receptor, Ste2p (for alpha-factor) or Ste3p (for a-factor), to the nuclear effectors, Ste12p and Mcm1p, via a MAPK cascade.
While these upstream kinases lead to tyrosine phosphorylation of the adaptor and activation of downstream effectors, they usually also activate other signaling pathways that can confound analysis of the specific role of the tyrosine phosphorylated adaptor protein.
Mis-regulation of Wnt signaling leads to the development of several human cancers, including colon carcinomas and melanoma [ 1 ] . Canonical Wnt signaling initiates in the binding of a Wnt ligand to its cell surface receptor, members of the frizzled gene family, along with the co-receptor LRP5/6 [ 2 3 ] , leading to changes in the activities of cytoplasmic effectors resulting in the stabilization of beta-catenin protein.
The 96-well plate was centrifuged at slow speed (1000 rpm) for 2-5 min to enable contact between effectors and targets.