Example sentences for: ecdysone

How can you use “ecdysone” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The ecdysone hormones do not affect mammalian physiology like glucocorticoids or progestins and are not known to be toxic or teratogenic like tetracycline [ 11 ] allowing their use in both developmental studies with transgenic animals as well as in the context of gene therapy and tumor biology studies in mature animals.

  • First, MCF7 cells were transfected with the pERV3 vector encoding both the RXR protein and an ecdysone/glucocorticoid receptor fusion protein using GenePorter (Gene Therapy Systems).

  • The use of ecdysone inducible transgene expression in vitro [ 8 9 ] and in transgenic mice [ 10 ] has recently been demonstrated.

  • Recently, the development of an inducible system based on the insect steroid ecdysone and the nuclear receptor that mediates its effect [ 7 ] has provided an alternative that may circumvent these limitations.

  • The popularity of the ecdysone inducible gene switch system has led us to investigate its characteristics as a regulator of transgene expression in tumor xenografts since to our knowledge, this has not yet been reported.


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