Words similar to ecdysone
Example sentences for: ecdysone
How can you use “ecdysone” in a sentence? Here are some example sentences to help you improve your vocabulary:
Our data suggests that in vivo induction of tumor transgene expression is feasible and reversible using an ecdysone switch and opens the avenue for the efficient functional characterization of many newly discovered genes as well as novel gene therapy approaches.
Recently, the development of an inducible system based on the insect steroid ecdysone and the nuclear receptor that mediates its effect [ 7 ] has provided an alternative that may circumvent these limitations.
[ 10 ] This finding may indicate that despite their use in a malignant context, the ecdysone constructs behave with similar kinetics to that in normal cells thus implying a general utility in studies of various histological tumor types.
The ecdysone hormones do not affect mammalian physiology like glucocorticoids or progestins and are not known to be toxic or teratogenic like tetracycline [ 11 ] allowing their use in both developmental studies with transgenic animals as well as in the context of gene therapy and tumor biology studies in mature animals.
GS-E is one of a family of diacylhydrazines that have been found to act as non-steroidal ecdysone mimics that can function as gene inducers [ 16 ] .