Words similar to ecdysone

Example sentences for: ecdysone

How can you use “ecdysone” in a sentence? Here are some example sentences to help you improve your vocabulary:

In the absence of pon A an ecdysone receptor/VP16 fusion protein actively represses the promoter leading to very low basal levels of expression.
Some precedence for a significant allosteric effect of one heterodimer partner on another is provided by the inability of the insect ecdysone receptor to bind its steroid ligand in the absence of its heterodimer partner USP [ 21 ] .
The ecdysone hormones do not affect mammalian physiology like glucocorticoids or progestins and are not known to be toxic or teratogenic like tetracycline [ 11 ] allowing their use in both developmental studies with transgenic animals as well as in the context of gene therapy and tumor biology studies in mature animals.
Treatment of the animals with ecdysone analog A/-(3-methoxy-2-ethylbenzoyl)-A/'-(3,5-dimethylbenzoyl)-A/'-tert-butyl hydrazine (GS-E) was then carried out with subsequent evaluation of in vivo gene expression.
Our data suggests that in vivo induction of tumor transgene expression is feasible and reversible using an ecdysone switch and opens the avenue for the efficient functional characterization of many newly discovered genes as well as novel gene therapy approaches.