Example sentences for: early-stage

How can you use “early-stage” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Filgrastim (recombinant methionyl human granulocyte colony-stimulating factor) has been shown to reduce the depth of the nadir ANC, shorten the duration of neutropenia, and reduce the risk of febrile neutropenia [ 3 ] , thereby maintaining chemotherapy dose [ 4 5 ] . Many patients with early-stage breast cancer do not receive the full chemotherapy dose intensity recommended in conventional adjuvant chemotherapy regimens [ 6 7 8 ] . Neutropenia is the primary reason for chemotherapy dose delays and reductions [ 1 6 7 ] .

  • This large increase has not been observed in other parts of California and appears to be limited to early-stage disease among white women aged 45-64 years at diagnosis.

  • However, the results show that TGF-β levels, as detected immunohistochemically, are not affected by tamoxifen or retinoids in this preclinical model of early-stage breast cancer.

  • Nearly all of the excess in overall rates was for early-stage (stage I/stage II) disease, for which Marin County rates (175 cases per 100,000; 95% CI, 165-187) were 31% higher than those for the rest of the SFBA (134 cases per 100,000; 95% CI, 131-136) and were 48% higher than those for other urban California counties (119 cases per 100,000; 95% CI, 117-120).

  • Such genes are important targets at early-stage carcinogenesis, where TGFβ has a tumor-suppressive rather than a tumor-promoting function [ 28 ] . In addition, e.g. p21 protein is not dectable in MDA-MB-231 cells [ 29 ] .


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