Example sentences for: early-born

How can you use “early-born” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Together with the above BrdU results, these observations indicate that disruption of Delta-Notch signaling causes excess neural precursors to be specified for early-born neuronal fates at the expense of later-born neuronal and glial fates, without interfering with mechanisms that specify early-born neuronal identity along the dorsoventral axis.

  • Second, the progenitors for cell types that normally arise late might instead develop identities appropriate for early-born cell types, resulting in an excess of some cell types and reduction of others.

  • In other words, early-born neurons are specified appropriately in dlA dx2 mutant embryos; what these embryos lack is the ability to regulate the number of cells specified for any particular fate.

  • Genetic disruption of Delta-Notch signaling causes precursors to prematurely terminate cell division and differentiate as early-born neurons, with identities appropriate to their cell body positions, at the expense of later born neurons and glia.

  • We also show that in dlA mutant embryos neural precursor cells prematurely cease dividing and differentiate as early-born neurons with identities appropriate for their positions within the spinal cord and that mutant embryos have reduced numbers of late-born neurons and glia.


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