Words similar to early-born
Example sentences for: early-born
How can you use “early-born” in a sentence? Here are some example sentences to help you improve your vocabulary:
Genetic disruption of Delta-Notch signaling causes precursors to prematurely terminate cell division and differentiate as early-born neurons, with identities appropriate to their cell body positions, at the expense of later born neurons and glia.
We also show that in dlA mutant embryos neural precursor cells prematurely cease dividing and differentiate as early-born neurons with identities appropriate for their positions within the spinal cord and that mutant embryos have reduced numbers of late-born neurons and glia.
In other words, early-born neurons are specified appropriately in dlA dx2 mutant embryos; what these embryos lack is the ability to regulate the number of cells specified for any particular fate.
Second, the progenitors for cell types that normally arise late might instead develop identities appropriate for early-born cell types, resulting in an excess of some cell types and reduction of others.
Similarly, expression of dominant negative Delta proteins caused formation of excess early-born neurons in the retina of frog [ 24] and chick [ 20] and in the neural plate of frog [ 25] and zebrafish [ 26, 27, 28], concomitant with decreased cell proliferation [ 20] and reduced numbers of late-born neurons [ 28].